!!AA_SCORING_MATRIX_RECT 1.0 Alternate symbol comparison table for the comparison of protein sequences. Similirity matrix based upon the analysis of amino acid substitutions after superposition of homologous protein structures (Risler, J. L., Delorme, M. O., Delacroix, H., and Henaut, A. [1988]. Amino Acid Substitutions in Structurally Related Proteins. A Pattern Recognition Approach. Determination of a New and Efficient Scoring Matrix. J. Mol. Biol. 204, 1019-1029). Only substitutions whose alpha carbon atoms are no more than 1.2 angstroms apart after superposition of structures were considered in constructing this matrix. February 20, 1996 14:56 .. { GAP_CREATE 40 GAP_EXTEND 5 } A B C D E F G H I K L M N P Q R S T V W Y Z A 22 8 -15 2 17 6 6 -6 17 14 13 10 13 -2 18 15 20 19 20 -9 2 18 B 8 15 -17 15 12 1 -1 -8 5 6 3 -3 15 -11 11 6 13 6 6 -13 -3 12 C -15 -17 22 -17 -15 -16 -17 -18 -16 -16 -15 -16 -16 -18 -14 -15 -13 -14 -14 -18 -11 -15 D 2 15 -17 22 10 -3 -4 -13 0 1 -2 -5 8 -12 6 -1 7 0 0 -14 -4 8 E 17 12 -15 10 22 6 3 -6 15 14 9 6 14 -1 21 19 18 16 16 -10 2 22 F 6 1 -16 -3 6 22 -4 -11 10 1 10 -2 4 -11 7 4 5 3 8 -9 20 7 G 6 -1 -17 -4 3 -4 22 -12 0 -1 -2 -4 2 -12 2 1 7 2 1 -13 -2 3 H -6 -8 -18 -13 -6 -11 -12 22 -8 -10 -9 -12 -3 -16 -5 -4 -4 -9 -7 -17 -8 -6 I 17 5 -16 0 15 10 0 -8 22 10 21 9 9 -6 14 14 16 16 22 -7 4 15 K 14 6 -16 1 14 1 -1 -10 10 22 7 4 10 -7 17 21 14 12 12 -11 5 16 L 13 3 -15 -2 9 10 -2 -9 21 7 22 18 8 -8 11 12 13 12 20 -8 5 10 M 10 -3 -16 -5 6 -2 -4 -12 9 4 18 22 0 -12 12 11 6 8 8 -13 -2 9 N 13 15 -16 8 14 4 2 -3 9 10 8 0 22 -10 16 12 19 11 11 -11 -1 15 P -2 -11 -18 -12 -1 -11 -12 -16 -6 -7 -8 -12 -10 22 -6 -3 -3 -5 -6 -16 -12 -4 Q 18 11 -14 6 21 7 2 -5 14 17 11 12 16 -6 22 20 18 17 15 -10 5 22 R 15 6 -15 -1 19 4 1 -4 14 21 12 11 12 -3 20 22 20 19 15 -8 8 20 S 20 13 -13 7 18 5 7 -4 16 14 13 6 19 -3 18 20 22 21 18 -8 4 18 T 19 6 -14 0 16 3 2 -9 16 12 12 8 11 -5 17 19 21 22 16 -10 3 17 V 20 6 -14 0 16 8 1 -7 22 12 20 8 11 -6 15 15 18 16 22 -7 3 16 W -9 -13 -18 -14 -10 -9 -13 -17 -7 -11 -8 -13 -11 -16 -10 -8 -8 -10 -7 22 -6 -10 Y 2 -3 -11 -4 2 20 -2 -8 4 5 5 -2 -1 -12 5 8 4 3 3 -6 22 4 Z 18 12 -15 8 22 7 3 -6 15 16 10 9 15 -4 22 20 18 17 16 -10 4 22