Profile High Intrst Gap Len A B C Ave SD --------------------------------------------------------------------------------------------.. profiledir:glu_carboxylation.prf 1.76 1.57 4.50 0.05 -0.0061 -0.4994 7.72 1.004 0.126 ! Vitamin K-dependent carboxylation domain. profiledir:phosphopantetheine.prf 1.85 1.63 4.50 0.05 -0.0066 -0.5890 5.75 1.000 0.141 ! Phosphopantetheine attachment site. profiledir:actinin_1.prf 1.81 1.61 4.50 0.05 -0.0069 -0.7342 6.17 1.001 0.135 ! Actinin-type actin-binding domain signature 1. profiledir:actinin_2.prf 1.94 1.71 4.50 0.05 -0.0053 -0.6666 7.11 1.008 0.156 ! Actinin-type actin-binding domain signature 2. profiledir:cofilin_tropomyosin.prf 1.79 1.59 4.50 0.05 -0.0066 -0.5889 8.73 1.003 0.131 ! Cofilin/tropomyosin-type actin-binding domain. profiledir:apple.prf 1.84 1.63 4.50 0.05 -0.0052 -0.8064 7.15 1.006 0.139 ! Apple domain. profiledir:band_41_1.prf 1.85 1.64 4.50 0.05 -0.0051 -0.7935 7.31 1.006 0.141 ! Band 4.1 family domain signature 1. profiledir:band_41_2.prf 1.93 1.70 4.50 0.05 -0.0045 -0.7748 7.51 1.003 0.155 ! Band 4.1 family domain signature 2. profiledir:kringle.prf 1.89 1.67 4.50 0.05 -0.0038 -0.9888 6.70 1.004 0.147 ! Kringle domain signature. profiledir:fibrin_ag_c_domain.prf 1.93 1.70 4.50 0.05 -0.0050 -0.7296 7.27 1.005 0.155 ! Fibrinogen beta and gamma chains C-terminal doma profiledir:fibronectin_2.prf 1.76 1.57 4.50 0.05 -0.0043 -0.9941 1.70 1.001 0.127 ! Type II fibronectin collagen-binding domain. profiledir:hemopexin.prf 1.75 1.56 4.50 0.05 -0.0059 -0.7550 6.64 1.002 0.124 ! Hemopexin domain signature. profiledir:c_type_lectin.prf 1.76 1.57 4.50 0.05 -0.0047 -1.0028 4.41 1.000 0.127 ! C-type lectin domain signature. profiledir:osteonectin_1.prf 1.88 1.66 4.50 0.05 -0.0036 -0.9316 9.58 1.007 0.145 ! Osteonectin domain signature 1. profiledir:osteonectin_2.prf 1.80 1.60 4.50 0.05 -0.0056 -0.7230 13.14 1.005 0.132 ! Osteonectin domain signature 2. profiledir:somatomedin_b.prf 1.94 1.71 4.50 0.05 -0.0040 -0.8516 8.18 1.006 0.156 ! Somatomedin B domain signature. profiledir:trefoil.prf 1.94 1.71 4.50 0.05 -0.0038 -0.7955 8.01 1.009 0.156 ! 'Trefoil' domain signature. profiledir:cbd_bacterial.prf 1.88 1.66 4.50 0.05 -0.0047 -0.6848 7.64 1.003 0.146 ! Cellulose-binding domain, bacterial type. profiledir:cbd_fungal.prf 1.99 1.75 4.50 0.05 -0.0037 -0.7609 8.78 1.004 0.165 ! Cellulose-binding domain, fungal type. profiledir:chitin_binding.prf 1.97 1.72 4.50 0.05 -0.0036 -0.8111 8.07 1.000 0.161 ! Chitin recognition or binding domain signature. profiledir:4_disulfide_core.prf 2.06 1.80 4.50 0.05 -0.0036 -0.7977 5.39 1.007 0.176 ! WAP-type 'four-disulfide core' domain signature. profiledir:dag_pe_binding_domain.prf 1.96 1.72 4.50 0.05 -0.0034 -0.9627 6.07 1.004 0.159 ! Phorbol esters / diacylglycerol binding domain. profiledir:c2_domain.prf 1.92 1.69 4.50 0.05 -0.0044 -0.8156 8.29 1.003 0.153 ! C2 domain signature. profiledir:zp_domain.prf 1.86 1.64 4.50 0.05 -0.0055 -0.6806 6.58 1.004 0.142 ! ZP domain signature. profiledir:homeobox.prf 1.88 1.66 4.50 0.05 -0.0044 -0.8233 6.19 1.001 0.147 ! 'Homeobox' domain signature. profiledir:antennapedia.prf 1.85 1.64 4.50 0.05 -0.0058 -0.7903 5.31 0.999 0.142 ! 'Homeobox' antennapedia-type protein signature. profiledir:engrailed.prf 1.96 1.72 4.50 0.05 -0.0058 -0.7117 9.24 1.005 0.159 ! 'Homeobox' engrailed-type protein signature. profiledir:paired_box.prf 1.88 1.66 4.50 0.05 -0.0056 -0.6144 12.88 1.008 0.145 ! 'Paired box' domain signature. profiledir:pou_1.prf 1.84 1.63 4.50 0.05 -0.0057 -0.6790 11.55 1.005 0.139 ! 'POU' domain signature 1. profiledir:pou_2.prf 1.82 1.62 4.50 0.05 -0.0063 -0.6853 12.65 0.999 0.137 ! 'POU' domain signature 2. profiledir:zinc_finger_c3hc4.prf 1.96 1.72 4.50 0.05 -0.0031 -0.9528 6.68 1.007 0.159 ! Zinc finger, C3HC4 type, signature. profiledir:steroid_finger.prf 1.91 1.68 4.50 0.05 -0.0038 -0.8482 8.56 1.007 0.150 ! Nuclear hormones receptors DNA-binding region si profiledir:gata_zn_finger.prf 1.96 1.72 4.50 0.05 -0.0040 -0.8542 9.44 1.003 0.159 ! GATA-type zinc finger domain. profiledir:parp_zn_finger.prf 1.79 1.59 4.50 0.05 -0.0068 -0.4696 14.08 1.003 0.131 ! Poly(ADP-ribose) polymerase zinc finger domain. profiledir:zn2_cy6_fungal.prf 2.05 1.79 4.50 0.05 -0.0028 -0.8891 5.88 1.003 0.174 ! Fungal Zn(2)-Cys(6) binuclear cluster domain. profiledir:myb_1.prf 1.86 1.65 4.50 0.05 -0.0052 -0.7827 5.39 0.999 0.144 ! Myb DNA-binding domain repeat signature 1. profiledir:myb_2.prf 1.82 1.61 4.50 0.05 -0.0071 -0.5379 6.99 1.000 0.136 ! Myb DNA-binding domain repeat signature 2. profiledir:helix_loop_helix.prf 1.96 1.72 4.50 0.05 -0.0039 -0.7979 4.30 0.997 0.160 ! Myc-type, 'helix-loop-helix' putative DNA-bindin profiledir:p53.prf 1.86 1.64 4.50 0.05 -0.0045 -0.7652 13.12 1.010 0.141 ! p53 tumor antigen signature. profiledir:cbfa_nfyb.prf 1.63 1.48 4.50 0.05 -0.0079 -0.4122 18.59 0.998 0.106 ! CBF-A/NF-YB subunit signature. profiledir:cbfb_nfya.prf 1.81 1.61 4.50 0.05 -0.0064 -0.5577 13.34 1.005 0.134 ! CBF-B/NF-YA subunit signature. profiledir:cold_shock.prf 1.77 1.58 4.50 0.05 -0.0075 -0.4716 14.57 1.000 0.128 ! 'Cold-shock' DNA-binding domain signature. profiledir:ctf_nfi.prf 1.88 1.66 4.50 0.05 -0.0063 -0.6493 14.07 1.002 0.146 ! CTF/NF-I signature. profiledir:ets_domain_1.prf 1.77 1.58 4.50 0.05 -0.0050 -0.8273 9.78 1.002 0.128 ! Ets-domain signature 1. profiledir:ets_domain_2.prf 1.79 1.59 4.50 0.05 -0.0082 -0.5269 11.84 1.000 0.131 ! Ets-domain signature 2. profiledir:fork_head_1.prf 1.77 1.58 4.50 0.05 -0.0061 -0.6397 11.97 1.002 0.128 ! Fork head domain signature 1. profiledir:irf.prf 1.87 1.65 4.50 0.05 -0.0066 -0.6016 11.00 1.000 0.145 ! IRF family signature. profiledir:lim_domain.prf 1.90 1.67 4.50 0.05 -0.0047 -0.8818 7.53 1.001 0.149 ! LIM domain. profiledir:srf.prf 1.92 1.69 4.50 0.05 -0.0054 -0.6143 10.14 1.004 0.153 ! SRF-type transcription factors DNA-binding and d profiledir:tfiis.prf 1.88 1.66 4.50 0.05 -0.0036 -0.8617 10.02 1.006 0.145 ! TFIIS cysteine-rich domain signature. profiledir:dead_atp_helicase.prf 1.89 1.67 4.50 0.05 -0.0051 -0.6860 7.19 1.005 0.148 ! DEAD-box subfamily ATP-dependent helicases signa profiledir:deah_atp_helicase.prf 1.91 1.68 4.50 0.05 -0.0062 -0.6581 5.24 1.005 0.151 ! DEAH-box subfamily ATP-dependent helicases signa profiledir:rnp_1.prf 1.72 1.54 4.50 0.05 -0.0080 -0.6236 4.30 0.996 0.120 ! Eukaryotic putative RNA-binding region RNP-1 sig profiledir:fibrillarin.prf 1.88 1.66 4.50 0.05 -0.0067 -0.6460 12.56 1.001 0.147 ! Fibrillarin signature. profiledir:hth_arac_family.prf 1.88 1.66 4.50 0.05 -0.0053 -0.7396 6.38 1.002 0.147 ! Bacterial regulatory proteins, araC family signa profiledir:hth_asnc_family.prf 1.37 1.28 4.50 0.05 -0.0071 -0.5370 7.56 0.999 0.062 ! Bacterial regulatory proteins, asnC family signa profiledir:hth_luxr_family.prf 1.99 1.74 4.50 0.05 -0.0047 -0.6885 4.12 1.005 0.164 ! Bacterial regulatory proteins, luxR family signa profiledir:hth_lysr_family.prf 1.53 1.40 4.50 0.05 -0.0047 -1.0970 1.90 1.000 0.088 ! Bacterial regulatory proteins, lysR family signa profiledir:hth_merr_family.prf 1.57 1.43 4.50 0.05 -0.0065 -0.9246 3.57 0.997 0.096 ! Bacterial regulatory proteins, merR family signa profiledir:antiterminators_bglg.prf 1.86 1.65 4.50 0.05 -0.0049 -0.7877 8.56 1.000 0.144 ! Transcriptional antiterminators bglG family sign profiledir:sigma54_interact_1.prf 1.96 1.72 4.50 0.05 -0.0048 -0.7179 7.33 1.003 0.159 ! Sigma-54 interaction domain ATP-binding region A profiledir:sigma54_interact_2.prf 1.75 1.56 4.50 0.05 -0.0069 -0.5919 12.30 0.998 0.125 ! Sigma-54 interaction domain ATP-binding region B profiledir:sigma54_interact_3.prf 1.99 1.74 4.50 0.05 -0.0048 -0.8058 5.75 1.002 0.164 ! Sigma-54 interaction domain C-terminal part sign profiledir:histone_like.prf 1.94 1.71 4.50 0.05 -0.0059 -0.6158 7.63 1.007 0.156 ! Bacterial histone-like DNA-binding proteins sign profiledir:histone_h2a.prf 1.60 1.45 4.50 0.05 -0.0081 -0.4277 14.72 1.002 0.099 ! Histone H2A signature. profiledir:histone_h2b.prf 1.92 1.69 4.50 0.05 -0.0054 -0.7600 10.26 1.004 0.152 ! Histone H2B signature. profiledir:histone_h3.prf 1.88 1.66 4.50 0.05 -0.0049 -0.7621 11.01 1.004 0.146 ! Histone H3 signature. profiledir:histone_h4.prf 1.84 1.63 4.50 0.05 -0.0053 -0.8234 10.83 1.000 0.140 ! Histone H4 signature. profiledir:hmg1_2.prf 1.68 1.51 4.50 0.05 -0.0070 -0.4650 19.12 1.001 0.113 ! HMG1/2 signature. profiledir:hmgi_y.prf 1.75 1.57 4.50 0.05 -0.0059 -0.4465 10.21 0.999 0.126 ! HMG-I and HMG-Y DNA-binding domain (A+T-hook). profiledir:hmg14_17.prf 1.88 1.66 4.50 0.05 -0.0066 -0.4740 10.81 1.007 0.145 ! HMG14 and HMG17 signature. profiledir:bromodomain.prf 1.97 1.73 4.50 0.05 -0.0053 -0.6379 8.29 1.002 0.162 ! Bromodomain. profiledir:chromo.prf 1.92 1.70 4.50 0.05 -0.0047 -0.7736 10.54 1.007 0.153 ! Chromo domain. profiledir:rcc1_1.prf 1.92 1.69 4.50 0.05 -0.0048 -0.7539 9.58 1.000 0.154 ! Regulator of chromosome condensation signature 1 profiledir:rcc1_2.prf 1.87 1.65 4.50 0.05 -0.0065 -0.5571 4.94 1.002 0.145 ! Regulator of chromosome condensation signature 2 profiledir:tp1.prf 1.92 1.69 4.50 0.05 -0.0039 -0.8510 11.71 1.005 0.152 ! Nuclear transition protein 1 signature. profiledir:ribosomal_l2.prf 1.84 1.63 4.50 0.05 -0.0066 -0.6040 7.36 1.003 0.139 ! Ribosomal protein L2 signature. profiledir:ribosomal_l3.prf 1.94 1.71 4.50 0.05 -0.0059 -0.6297 7.22 1.006 0.156 ! Ribosomal protein L3 signature. profiledir:ribosomal_l5.prf 1.92 1.69 4.50 0.05 -0.0045 -0.7911 7.44 1.003 0.153 ! Ribosomal protein L5 signature. profiledir:ribosomal_l6_1.prf 1.96 1.73 4.50 0.05 -0.0055 -0.5801 7.17 1.005 0.160 ! Ribosomal protein L6 signature 1. profiledir:ribosomal_l9.prf 1.97 1.73 4.50 0.05 -0.0047 -0.6835 8.69 1.004 0.161 ! Ribosomal protein L9 signature. profiledir:ribosomal_l11.prf 1.81 1.61 4.50 0.05 -0.0077 -0.4146 8.01 1.004 0.134 ! Ribosomal protein L11 signature. profiledir:ribosomal_l14.prf 1.86 1.64 4.50 0.05 -0.0073 -0.4521 8.54 0.999 0.143 ! Ribosomal protein L14 signature. profiledir:ribosomal_l15.prf 1.63 1.48 4.50 0.05 -0.0063 -0.7664 8.32 0.998 0.106 ! Ribosomal protein L15 signature. profiledir:ribosomal_l16_1.prf 1.93 1.70 4.50 0.05 -0.0053 -0.7195 10.62 1.003 0.154 ! Ribosomal protein L16 signature 1. profiledir:ribosomal_l22.prf 1.94 1.71 4.50 0.05 -0.0046 -0.7746 6.08 1.004 0.156 ! Ribosomal protein L22 signature. profiledir:ribosomal_l23.prf 1.84 1.63 4.50 0.05 -0.0043 -0.9663 4.37 0.997 0.141 ! Ribosomal protein L23 signature. profiledir:ribosomal_l29.prf 1.90 1.68 4.50 0.05 -0.0056 -0.6742 7.59 1.000 0.150 ! Ribosomal protein L29 signature. profiledir:ribosomal_l30.prf 1.72 1.54 4.50 0.05 -0.0077 -0.5189 4.98 1.001 0.119 ! Ribosomal protein L30 signature. profiledir:ribosomal_l33.prf 1.97 1.72 4.50 0.05 -0.0042 -0.9105 8.03 1.000 0.161 ! Ribosomal protein L33 signature. profiledir:ribosomal_l19e.prf 2.00 1.75 4.50 0.05 -0.0052 -0.6378 10.16 1.007 0.165 ! Ribosomal protein L19e signature. profiledir:ribosomal_l32e.prf 1.87 1.65 4.50 0.05 -0.0060 -0.6083 10.39 1.005 0.144 ! Ribosomal protein L32e signature. profiledir:ribosomal_l46e.prf 1.93 1.70 4.50 0.05 -0.0039 -0.9222 8.04 1.009 0.154 ! Ribosomal protein L46e signature. profiledir:ribosomal_s3_1.prf 1.83 1.62 4.50 0.05 -0.0059 -0.7929 6.27 1.001 0.138 ! Ribosomal protein S3 signature 1. profiledir:ribosomal_s4.prf 1.30 1.22 4.50 0.05 -0.0060 -0.5720 24.37 0.996 0.050 ! Ribosomal protein S4 signature. profiledir:ribosomal_s5.prf 1.91 1.68 4.50 0.05 -0.0057 -0.5305 9.94 1.005 0.151 ! Ribosomal protein S5 signature. profiledir:ribosomal_s7.prf 1.94 1.71 4.50 0.05 -0.0049 -0.6765 6.28 1.008 0.155 ! Ribosomal protein S7 signature. profiledir:ribosomal_s8.prf 1.92 1.69 4.50 0.05 -0.0049 -0.7717 7.04 1.005 0.153 ! Ribosomal protein S8 signature. profiledir:ribosomal_s9.prf 1.85 1.64 4.50 0.05 -0.0046 -0.8114 8.45 1.006 0.141 ! Ribosomal protein S9 signature. profiledir:ribosomal_s10.prf 1.94 1.71 4.50 0.05 -0.0051 -0.6665 7.01 1.005 0.156 ! Ribosomal protein S10 signature. profiledir:ribosomal_s11.prf 1.93 1.70 4.50 0.05 -0.0047 -0.7590 8.23 1.008 0.154 ! Ribosomal protein S11 signature. profiledir:ribosomal_s12.prf 1.84 1.63 4.50 0.05 -0.0058 -0.6685 8.18 1.005 0.139 ! Ribosomal protein S12 signature. profiledir:ribosomal_s13.prf 1.92 1.69 4.50 0.05 -0.0047 -0.7639 9.14 1.006 0.153 ! Ribosomal protein S13 signature. profiledir:ribosomal_s14.prf 1.93 1.70 4.50 0.05 -0.0043 -0.8224 6.42 1.004 0.154 ! Ribosomal protein S14 signature. profiledir:ribosomal_s15.prf 1.98 1.74 4.50 0.05 -0.0046 -0.6467 7.35 1.004 0.163 ! Ribosomal protein S15 signature. profiledir:ribosomal_s17.prf 1.92 1.69 4.50 0.05 -0.0062 -0.6341 6.68 1.000 0.153 ! Ribosomal protein S17 signature. profiledir:ribosomal_s18.prf 1.91 1.68 4.50 0.05 -0.0039 -0.8752 9.39 1.002 0.151 ! Ribosomal protein S18 signature. profiledir:ribosomal_s19.prf 1.95 1.71 4.50 0.05 -0.0079 -0.5304 7.93 1.000 0.158 ! Ribosomal protein S19 signature. profiledir:ribosomal_s4e.prf 1.94 1.70 4.50 0.05 -0.0038 -0.8680 7.88 1.007 0.155 ! Ribosomal protein S4e signature. profiledir:ribosomal_s6e.prf 1.83 1.63 4.50 0.05 -0.0071 -0.5593 10.02 1.000 0.139 ! Ribosomal protein S6e signature. profiledir:ribosomal_s19e.prf 1.89 1.67 4.50 0.05 -0.0072 -0.5272 9.32 1.003 0.148 ! Ribosomal protein S19e signature. profiledir:ribosomal_s24e.prf 1.93 1.70 4.50 0.05 -0.0047 -0.7723 9.62 1.006 0.154 ! Ribosomal protein S24e signature. profiledir:dna_mismatch_repair_1.prf 1.94 1.71 4.50 0.05 -0.0052 -0.7350 9.26 1.004 0.156 ! DNA mismatch repair proteins mutL / hexB / PMS1 profiledir:dna_mismatch_repair_2.prf 1.91 1.69 4.50 0.05 -0.0068 -0.6312 8.14 1.002 0.152 ! DNA mismatch repair proteins mutS family signatu profiledir:recf_1.prf 1.91 1.68 4.50 0.05 -0.0041 -0.7819 9.78 1.003 0.151 ! RecF protein signature 1. profiledir:recf_2.prf 1.80 1.60 4.50 0.05 -0.0088 -0.4185 10.40 0.999 0.134 ! RecF protein signature 2. profiledir:sasp_1.prf 1.77 1.58 4.50 0.05 -0.0066 -0.5836 10.01 1.002 0.128 ! Small, acid-soluble spore proteins, alpha/beta t profiledir:sasp_2.prf 1.84 1.63 4.50 0.05 -0.0066 -0.6304 9.10 1.004 0.139 ! Small, acid-soluble spore proteins, alpha/beta t profiledir:adh_zinc.prf 1.81 1.60 4.50 0.05 -0.0069 -0.5420 6.73 1.001 0.134 ! Zinc-containing alcohol dehydrogenases signature profiledir:adh_iron.prf 1.95 1.71 4.50 0.05 -0.0055 -0.6510 9.90 1.003 0.157 ! Iron-containing alcohol dehydrogenases signature profiledir:adh_short.prf 1.93 1.70 4.50 0.05 -0.0057 -0.7269 4.73 0.999 0.155 ! Short-chain alcohol dehydrogenase family signatu profiledir:aldoketo_reductase_2.prf 1.86 1.65 4.50 0.05 -0.0062 -0.6141 7.76 1.000 0.144 ! Aldo/keto reductase family signature 2. profiledir:aldoketo_reductase_3.prf 1.85 1.64 4.50 0.05 -0.0061 -0.6539 8.61 1.000 0.142 ! Aldo/keto reductase family putative active site profiledir:hisol_dehydrogenase.prf 1.86 1.65 4.50 0.05 -0.0070 -0.4500 12.22 1.006 0.143 ! Histidinol dehydrogenase active site. profiledir:l_ldh.prf 1.89 1.67 4.50 0.05 -0.0048 -0.7669 6.93 1.006 0.148 ! L-lactate dehydrogenase active site. profiledir:d_2_hydroxyacid_dh_1.prf 1.56 1.42 4.50 0.05 -0.0062 -0.7381 2.33 1.000 0.093 ! D-isomer specific 2-hydroxyacid dehydrogenases N profiledir:d_2_hydroxyacid_dh_2.prf 1.85 1.64 4.50 0.05 -0.0080 -0.4367 7.01 1.001 0.141 ! D-isomer specific 2-hydroxyacid dehydrogenases s profiledir:d_2_hydroxyacid_dh_3.prf 1.96 1.72 4.50 0.05 -0.0050 -0.6692 7.80 1.003 0.159 ! D-isomer specific 2-hydroxyacid dehydrogenases s profiledir:hmg_coa_reductase_1.prf 1.91 1.68 4.50 0.05 -0.0055 -0.7008 7.95 1.002 0.151 ! Hydroxymethylglutaryl-coenzyme A reductases sign profiledir:hmg_coa_reductase_2.prf 1.87 1.65 4.50 0.05 -0.0052 -0.6768 7.90 1.002 0.145 ! Hydroxymethylglutaryl-coenzyme A reductases sign profiledir:3hcdh.prf 1.85 1.63 4.50 0.05 -0.0069 -0.6039 8.91 1.000 0.141 ! 3-hydroxyacyl-CoA dehydrogenase signature. profiledir:mdh.prf 1.88 1.66 4.50 0.05 -0.0079 -0.4590 7.07 0.999 0.147 ! Malate dehydrogenase active site signature. profiledir:malic_enzymes.prf 1.85 1.64 4.50 0.05 -0.0079 -0.4214 11.18 1.004 0.141 ! Malic enzymes signature. profiledir:6pgd.prf 1.86 1.64 4.50 0.05 -0.0059 -0.6443 10.30 1.003 0.142 ! 6-phosphogluconate dehydrogenase signature. profiledir:g6p_dehydrogenase.prf 1.46 1.34 4.50 0.05 -0.0081 -0.4574 21.04 0.999 0.076 ! Glucose-6-phosphate dehydrogenase active site. profiledir:imp_dh_gmp_red.prf 2.00 1.75 4.50 0.05 -0.0054 -0.5329 9.57 1.005 0.165 ! IMP dehydrogenase / GMP reductase signature. profiledir:bacterial_pqq_1.prf 1.90 1.68 4.50 0.05 -0.0064 -0.5709 8.94 0.999 0.151 ! Bacterial quinoprotein dehydrogenases signature profiledir:bacterial_pqq_2.prf 1.84 1.63 4.50 0.05 -0.0056 -0.6782 9.50 1.001 0.139 ! Bacterial quinoprotein dehydrogenases signature profiledir:fmn_hydroxy_acid_dh.prf 1.96 1.72 4.50 0.05 -0.0042 -0.7932 8.00 1.002 0.159 ! FMN-dependent alpha-hydroxy acid dehydrogenases profiledir:gmc_oxred_1.prf 1.79 1.59 4.50 0.05 -0.0061 -0.6658 9.99 1.000 0.131 ! GMC oxidoreductases signature 1. profiledir:gmc_oxred_2.prf 1.99 1.74 4.50 0.05 -0.0052 -0.5836 8.40 1.008 0.163 ! GMC oxidoreductases signature 2. profiledir:molybdopterin_euk.prf 1.73 1.55 4.50 0.05 -0.0062 -0.5372 9.80 1.003 0.121 ! Eukaryotic molybdopterin oxidoreductases signatu profiledir:molybdopterin_prok_1.prf 1.88 1.66 4.50 0.05 -0.0045 -0.8227 6.63 1.008 0.145 ! Prokaryotic molybdopterin oxidoreductases signat profiledir:molybdopterin_prok_2.prf 1.96 1.72 4.50 0.05 -0.0046 -0.7150 6.86 1.004 0.160 ! Prokaryotic molybdopterin oxidoreductases signat profiledir:aldehyde_dehydr_glu.prf 1.86 1.64 4.50 0.05 -0.0068 -0.6127 5.99 0.997 0.144 ! Aldehyde dehydrogenases glutamic acid active sit profiledir:aldehyde_dehydr_cys.prf 1.87 1.66 4.50 0.05 -0.0044 -0.8756 6.19 1.003 0.145 ! Aldehyde dehydrogenases cysteine active site. profiledir:gapdh.prf 1.81 1.61 4.50 0.05 -0.0063 -0.5928 6.99 1.004 0.135 ! Glyceraldehyde 3-phosphate dehydrogenase active profiledir:frd_sdh_fad_binding.prf 1.90 1.67 4.50 0.05 -0.0058 -0.6503 7.53 1.002 0.149 ! Fumarate reductase / succinate dehydrogenase FAD profiledir:acyl_coa_dh_1.prf 1.97 1.73 4.50 0.05 -0.0054 -0.5963 8.64 1.006 0.161 ! Acyl-CoA dehydrogenases signature 1. profiledir:acyl_coa_dh_2.prf 1.93 1.70 4.50 0.05 -0.0056 -0.6150 8.59 1.001 0.155 ! Acyl-CoA dehydrogenases signature 2. profiledir:glf_dehydrogenase.prf 1.79 1.59 4.50 0.05 -0.0062 -0.7070 7.36 1.000 0.132 ! Glutamate / Leucine / Phenylalanine dehydrogenas profiledir:dao.prf 1.80 1.60 4.50 0.05 -0.0057 -0.7676 11.36 0.998 0.134 ! D-amino acid oxidase signature. profiledir:p5cr.prf 1.63 1.47 4.50 0.05 -0.0050 -0.8959 2.95 1.001 0.105 ! Delta 1-pyrroline-5-carboxylate reductase signat profiledir:dhfr.prf 1.81 1.61 4.50 0.05 -0.0046 -0.8952 5.41 0.999 0.135 ! Dihydrofolate reductase signature. profiledir:pyridine_redox_1.prf 1.83 1.62 4.50 0.05 -0.0045 -0.7973 7.12 0.999 0.139 ! Pyridine nucleotide-disulphide oxidoreductases c profiledir:pyridine_redox_2.prf 1.93 1.70 4.50 0.05 -0.0055 -0.6406 10.32 1.005 0.155 ! Pyridine nucleotide-disulphide oxidoreductases c profiledir:complex1_nd1_1.prf 1.36 1.26 4.50 0.05 -0.0069 -0.4716 10.64 0.995 0.060 ! Respiratory-chain NADH dehydrogenase subunit 1 s profiledir:complex1_nd1_2.prf 1.79 1.59 4.50 0.05 -0.0057 -0.7387 8.94 1.000 0.131 ! Respiratory-chain NADH dehydrogenase subunit 1 s profiledir:complex1_30k.prf 1.95 1.71 4.50 0.05 -0.0057 -0.6585 8.40 1.001 0.158 ! Respiratory chain NADH dehydrogenase 30 Kd subun profiledir:complex1_49k.prf 1.90 1.68 4.50 0.05 -0.0040 -0.8695 8.38 1.005 0.150 ! Respiratory chain NADH dehydrogenase 49 Kd subun profiledir:complex1_51k_1.prf 1.83 1.62 4.50 0.05 -0.0061 -0.6439 13.11 1.004 0.138 ! Respiratory-chain NADH dehydrogenase 51 Kd subun profiledir:complex1_51k_2.prf 1.92 1.69 4.50 0.05 -0.0048 -0.8382 9.11 1.004 0.153 ! Respiratory-chain NADH dehydrogenase 51 Kd subun profiledir:complex1_75k_1.prf 1.87 1.65 4.50 0.05 -0.0053 -0.6855 10.59 1.002 0.145 ! Respiratory-chain NADH dehydrogenase 75 Kd subun profiledir:complex1_75k_2.prf 1.94 1.70 4.50 0.05 -0.0056 -0.7966 9.53 1.006 0.155 ! Respiratory-chain NADH dehydrogenase 75 Kd subun profiledir:complex1_75k_3.prf 1.81 1.61 4.50 0.05 -0.0059 -0.7552 9.93 1.001 0.135 ! Respiratory-chain NADH dehydrogenase 75 Kd subun profiledir:nir_sir.prf 1.90 1.67 4.50 0.05 -0.0056 -0.6415 7.04 1.004 0.149 ! Nitrite reductases and sulfite reductase putativ profiledir:uricase.prf 1.97 1.73 4.50 0.05 -0.0048 -0.7791 9.81 1.006 0.161 ! Uricase signature. profiledir:cox1.prf 1.86 1.65 4.50 0.05 -0.0043 -0.8029 8.39 1.003 0.143 ! Cytochrome c oxidase subunit I, copper B binding profiledir:cox2.prf 1.72 1.54 4.50 0.05 -0.0076 -0.6780 8.66 1.000 0.120 ! Cytochrome c oxidase subunit II, copper A bindin profiledir:multicopper_oxidase1.prf 1.92 1.69 4.50 0.05 -0.0065 -0.5791 5.06 1.000 0.153 ! Multicopper oxidases signature 1. profiledir:multicopper_oxidase2.prf 1.91 1.69 4.50 0.05 -0.0048 -0.8088 6.08 1.003 0.152 ! Multicopper oxidases signature 2. profiledir:peroxidase_1.prf 1.95 1.72 4.50 0.05 -0.0058 -0.6141 3.85 1.005 0.158 ! Peroxidases proximal heme-ligand signature. profiledir:peroxidase_2.prf 1.96 1.72 4.50 0.05 -0.0050 -0.7096 4.81 1.006 0.159 ! Peroxidases active site signature. profiledir:catalase_1.prf 1.78 1.58 4.50 0.05 -0.0058 -0.7342 9.28 1.002 0.129 ! Catalase proximal heme-ligand signature. profiledir:catalase_2.prf 1.83 1.62 4.50 0.05 -0.0057 -0.6605 9.89 1.003 0.138 ! Catalase proximal active site signature. profiledir:glutathione_peroxid_1.prf 1.81 1.61 4.50 0.05 -0.0062 -0.6407 9.75 1.002 0.134 ! Glutathione peroxidases selenocysteine active si profiledir:lipoxygenase_2.prf 1.84 1.63 4.50 0.05 -0.0059 -0.6736 10.83 1.003 0.139 ! Lipoxygenases, putative iron-binding region sign profiledir:extradiol_dioxygenas.prf 1.90 1.68 4.50 0.05 -0.0064 -0.5549 6.90 1.002 0.150 ! Extradiol ring-cleavage dioxygenases signature. profiledir:intradiol_dioxygenas.prf 1.44 1.33 4.50 0.05 -0.0060 -0.4070 6.29 0.999 0.073 ! Intradiol ring-cleavage dioxygenases signature. profiledir:ring_hydroxyl_alpha.prf 1.94 1.71 4.50 0.05 -0.0057 -0.6669 10.01 1.005 0.156 ! Bacterial ring hydroxylating dioxygenases alpha- profiledir:bacterial_luciferase.prf 1.83 1.62 4.50 0.05 -0.0086 -0.4197 8.72 0.996 0.139 ! Bacterial luciferase subunits signature. profiledir:biopterin_hydroxyl.prf 1.88 1.66 4.50 0.05 -0.0051 -0.7570 11.82 1.006 0.145 ! Biopterin-dependent aromatic amino acid hydroxyl profiledir:cu2_monooxygenase_1.prf 1.84 1.63 4.50 0.05 -0.0060 -0.7143 9.31 1.005 0.139 ! Copper type II, ascorbate-dependent monooxygenas profiledir:cu2_monooxygenase_2.prf 1.95 1.71 4.50 0.05 -0.0060 -0.5821 8.15 1.008 0.157 ! Copper type II, ascorbate-dependent monooxygenas profiledir:tyrosinase_1.prf 1.75 1.56 4.50 0.05 -0.0076 -0.4576 10.59 1.000 0.125 ! Tyrosinase CuA-binding region signature. profiledir:tyrosinase_2.prf 1.90 1.68 4.50 0.05 -0.0050 -0.6922 6.02 1.002 0.150 ! Tyrosinase and hemocyanins CuB-binding region si profiledir:fatty_acid_desatur_1.prf 1.92 1.69 4.50 0.05 -0.0064 -0.6178 10.23 1.005 0.152 ! Fatty acid desaturases family 1 signature. profiledir:fatty_acid_desatur_2.prf 1.87 1.65 4.50 0.05 -0.0079 -0.4807 10.20 1.001 0.144 ! Fatty acid desaturases family 2 signature. profiledir:cytochrome_p450.prf 1.80 1.60 4.50 0.05 -0.0048 -0.8651 5.58 0.999 0.133 ! Cytochrome P450 cysteine heme-iron ligand signat profiledir:heme_oxygenase.prf 1.90 1.67 4.50 0.05 -0.0053 -0.8056 11.97 1.001 0.149 ! Heme oxygenase signature. profiledir:sod_cu_zn_1.prf 1.86 1.65 4.50 0.05 -0.0070 -0.5490 6.39 1.002 0.143 ! Copper/Zinc superoxide dismutase signature 1. profiledir:sod_cu_zn_2.prf 1.76 1.57 4.50 0.05 -0.0057 -0.7585 7.57 1.002 0.127 ! Copper/Zinc superoxide dismutase signature 2. profiledir:sod_mn.prf 1.86 1.64 4.50 0.05 -0.0037 -0.9233 8.14 1.001 0.143 ! Manganese and iron superoxide dismutases signatu profiledir:ribored_large.prf 1.93 1.70 4.50 0.05 -0.0056 -0.6690 7.94 1.003 0.154 ! Ribonucleotide reductase large subunit signature profiledir:ribored_small.prf 1.87 1.66 4.50 0.05 -0.0056 -0.6213 6.76 1.003 0.145 ! Ribonucleotide reductase small subunit signature profiledir:nitrogenase_1_2.prf 1.93 1.69 4.50 0.05 -0.0052 -0.7825 5.67 1.001 0.154 ! Nitrogenases component 1 alpha and beta subunits profiledir:nifh_frxc_2.prf 1.81 1.61 4.50 0.05 -0.0079 -0.5225 10.53 1.003 0.135 ! NifH/frxC family signature 2. profiledir:ni_hgenase_l_1.prf 1.93 1.70 4.50 0.05 -0.0055 -0.6383 8.53 1.006 0.154 ! Nickel-dependent hydrogenases large subunit sign profiledir:ni_hgenase_l_2.prf 1.91 1.68 4.50 0.05 -0.0047 -0.7645 6.69 1.004 0.151 ! Nickel-dependent hydrogenases large subunit sign profiledir:thymidylate_synthase.prf 1.74 1.55 4.50 0.05 -0.0068 -0.6078 9.93 1.001 0.123 ! Thymidylate synthase active site. profiledir:mgmt.prf 1.89 1.67 4.50 0.05 -0.0050 -0.7473 8.45 1.005 0.147 ! Methylated-DNA--protein-cysteine methyltransfera profiledir:n6_mtase.prf 2.04 1.78 4.50 0.05 -0.0043 -0.6736 3.40 1.007 0.172 ! N-6 Adenine-specific DNA methylases signature. profiledir:n4_mtase.prf 1.84 1.63 4.50 0.05 -0.0062 -0.6683 7.00 1.002 0.140 ! N-4 cytosine-specific DNA methylases signature. profiledir:c5_mtase_1.prf 1.81 1.61 4.50 0.05 -0.0047 -0.7847 5.59 1.004 0.135 ! C-5 cytosine-specific DNA methylases active site profiledir:c5_mtase_2.prf 1.88 1.66 4.50 0.05 -0.0064 -0.6748 4.63 1.000 0.146 ! C-5 cytosine-specific DNA methylases C-terminal profiledir:ser_hydroxymethyltrf.prf 1.87 1.65 4.50 0.05 -0.0058 -0.6092 10.73 1.004 0.144 ! Serine hydroxymethyltransferase pyridoxal-phosph profiledir:gart.prf 1.83 1.62 4.50 0.05 -0.0074 -0.4620 8.90 1.003 0.138 ! Phosphoribosylglycinamide formyltransferase acti profiledir:carbamoyltransferase.prf 1.95 1.71 4.50 0.05 -0.0045 -0.8092 6.16 1.005 0.157 ! Aspartate and ornithine carbamoyltransferases si profiledir:acyltransf_c_1.prf 1.91 1.68 4.50 0.05 -0.0059 -0.7102 8.72 1.004 0.151 ! Acyltransferases ChoActase / COT / CPT-II family profiledir:acyltransf_c_2.prf 1.82 1.61 4.50 0.05 -0.0062 -0.6606 9.55 1.001 0.136 ! Acyltransferases ChoActase / COT / CPT-II family profiledir:thiolase_1.prf 1.98 1.74 4.50 0.05 -0.0051 -0.5724 7.43 1.007 0.162 ! Thiolases acyl-enzyme intermediate signature. profiledir:thiolase_3.prf 1.83 1.62 4.50 0.05 -0.0055 -0.8178 7.94 1.001 0.138 ! Thiolases active site. profiledir:cat.prf 1.89 1.67 4.50 0.05 -0.0044 -0.8370 7.76 1.004 0.148 ! Chloramphenicol acetyltransferase active site. profiledir:cyse_laca_nodl.prf 1.92 1.69 4.50 0.05 -0.0054 -0.5538 8.84 1.004 0.152 ! cysE / lacA / nodL acetyltransferases signature. profiledir:b_ketoacyl_synthase.prf 1.98 1.74 4.50 0.05 -0.0053 -0.5344 5.88 1.006 0.163 ! Beta-ketoacyl synthases active site. profiledir:chalcone_synth.prf 1.80 1.60 4.50 0.05 -0.0078 -0.5756 13.31 1.000 0.134 ! Chalcone and stilbene synthases active site. profiledir:g_glu_transpeptidase.prf 1.85 1.64 4.50 0.05 -0.0063 -0.5280 11.66 1.003 0.141 ! Gamma-glutamyltranspeptidase signature. profiledir:transglutaminases.prf 1.81 1.61 4.50 0.05 -0.0074 -0.4873 12.27 1.003 0.134 ! Transglutaminases active site. profiledir:phosphorylase.prf 1.91 1.68 4.50 0.05 -0.0042 -0.7735 11.10 1.001 0.151 ! Phosphorylase pyridoxal-phosphate attachment sit profiledir:udpgt.prf 1.93 1.70 4.50 0.05 -0.0048 -0.7701 3.88 1.003 0.155 ! UDP-glucoronosyl and UDP-glucosyl transferases s profiledir:pur_pyr_pr_transfer.prf 1.99 1.74 4.50 0.05 -0.0053 -0.5830 4.58 1.003 0.164 ! Purine/pyrimidine phosphoribosyl transferases si profiledir:gatase_type_i.prf 1.69 1.52 4.50 0.05 -0.0086 -0.4172 9.88 0.996 0.116 ! Glutamine amidotransferases class-I active site. profiledir:adomet_synthetase_2.prf 1.90 1.68 4.50 0.05 -0.0051 -0.7799 11.69 1.002 0.150 ! S-Adenosylmethionine synthetase signature 2. profiledir:polyprenyl_synthet_2.prf 1.92 1.69 4.50 0.05 -0.0065 -0.6566 6.41 0.999 0.153 ! Polyprenyl synthetases signature 2. profiledir:epsp_synthase.prf 1.87 1.65 4.50 0.05 -0.0054 -0.8584 6.97 0.995 0.145 ! EPSP synthase active site. profiledir:asp_aminotransferase.prf 1.96 1.72 4.50 0.05 -0.0050 -0.7686 8.35 1.005 0.159 ! Aspartate aminotransferases pyridoxal-phosphate profiledir:aa_transfer_class_2.prf 1.88 1.66 4.50 0.05 -0.0059 -0.6778 5.49 1.001 0.146 ! Aminotransferases class-II pyridoxal-phosphate a profiledir:aa_transfer_class_3.prf 1.77 1.58 4.50 0.05 -0.0071 -0.5153 8.38 0.999 0.128 ! Aminotransferases class-III pyridoxal-phosphate profiledir:p_ser_aminotransfer.prf 1.89 1.67 4.50 0.05 -0.0046 -0.7948 11.19 1.006 0.148 ! Phosphoserine aminotransferase signature. profiledir:hexokinases.prf 1.85 1.64 4.50 0.05 -0.0067 -0.5618 10.97 1.001 0.141 ! Hexokinases signature. profiledir:galactokinase.prf 1.95 1.71 4.50 0.05 -0.0049 -0.7145 7.91 1.006 0.157 ! Galactokinase signature. profiledir:ghmp_kinases_atp.prf 1.94 1.71 4.50 0.05 -0.0046 -0.6961 5.64 1.001 0.157 ! GHMP kinases putative ATP-binding domain. profiledir:phosphofructokinase.prf 1.95 1.71 4.50 0.05 -0.0052 -0.6819 6.99 1.006 0.157 ! Phosphofructokinase signature. profiledir:pfkb_kinases_1.prf 1.93 1.70 4.50 0.05 -0.0052 -0.5612 6.70 1.004 0.154 ! pfkB family of carbohydrate kinases signature 1. profiledir:pfkb_kinases_2.prf 1.94 1.71 4.50 0.05 -0.0063 -0.5169 5.08 1.004 0.156 ! pfkB family of carbohydrate kinases signature 2. profiledir:phosphoribulokinase.prf 1.95 1.71 4.50 0.05 -0.0042 -0.8063 9.00 1.005 0.157 ! Phosphoribulokinase signature. profiledir:tk_cellular_type.prf 1.83 1.62 4.50 0.05 -0.0046 -0.9185 6.38 1.001 0.138 ! Thymidine kinase cellular-type signature. profiledir:prok_carb_kinases.prf 1.93 1.70 4.50 0.05 -0.0058 -0.6321 7.29 1.000 0.155 ! Prokaryotic carbohydrate kinases signature. profiledir:protein_kinase_tyr.prf 1.80 1.60 4.50 0.05 -0.0061 -0.6760 6.11 0.994 0.134 ! Tyrosine protein kinases specific active-site si profiledir:pyruvate_kinase.prf 1.80 1.60 4.50 0.05 -0.0078 -0.4692 10.12 1.001 0.133 ! Pyruvate kinase active site signature. profiledir:pglycerate_kinase.prf 1.99 1.75 4.50 0.05 -0.0047 -0.7114 7.00 1.007 0.164 ! Phosphoglycerate kinase signature. profiledir:aspartokinase.prf 1.87 1.65 4.50 0.05 -0.0060 -0.7792 6.42 1.000 0.145 ! Aspartokinase signature. profiledir:guanido_kinase.prf 1.61 1.46 4.50 0.05 -0.0065 -0.7445 10.42 1.000 0.102 ! ATP:guanido phosphotransferases active site. profiledir:pts_hpr_his.prf 1.95 1.71 4.50 0.05 -0.0041 -0.8624 6.33 1.003 0.157 ! PTS HPR component histidine phosphorylation site profiledir:pts_hpr_ser.prf 1.82 1.61 4.50 0.05 -0.0082 -0.4059 8.66 1.002 0.136 ! PTS HPR component serine phosphorylation site si profiledir:pts_eii_eiii_1.prf 1.96 1.72 4.50 0.05 -0.0055 -0.6059 8.70 1.009 0.159 ! PTS EII/EIII components phosphorylation site sig profiledir:pts_eii_eiii_2.prf 1.70 1.52 4.50 0.05 -0.0073 -0.5875 7.35 1.002 0.116 ! PTS EII/EIII components phosphorylation site sig profiledir:adenylate_kinase.prf 1.85 1.64 4.50 0.05 -0.0067 -0.6684 6.88 0.999 0.142 !prositedir:0104.pdoc Adenylate kinase signature. profiledir:ndp_kinases.prf 1.92 1.69 4.50 0.05 -0.0057 -0.6770 9.23 1.005 0.153 ! Nucleoside diphosphate kinases active site. profiledir:prpp_synthetase.prf 1.93 1.70 4.50 0.05 -0.0063 -0.6681 10.59 0.999 0.155 ! Phosphoribosyl pyrophosphate synthetase signatur profiledir:rna_pol_phage.prf 1.84 1.63 4.50 0.05 -0.0064 -0.5794 7.76 1.003 0.139 ! Bacteriophage-type RNA polymerase family active profiledir:rna_pol_30kd.prf 1.87 1.65 4.50 0.05 -0.0059 -0.7109 9.88 1.003 0.144 ! Eukaryotic RNA polymerases 30 to 40 Kd subunits profiledir:dna_polymerase_a.prf 1.93 1.70 4.50 0.05 -0.0052 -0.7060 6.28 1.002 0.155 ! DNA polymerase family A signature. profiledir:dna_polymerase_b.prf 1.96 1.72 4.50 0.05 -0.0038 -0.8702 4.71 1.003 0.159 ! DNA polymerase family B signature. profiledir:dna_polymerase_x.prf 1.84 1.63 4.50 0.05 -0.0088 -0.4113 11.40 1.003 0.140 ! DNA polymerase family X signature. profiledir:gal-p-udp-transfer.prf 1.66 1.49 4.50 0.05 -0.0090 -0.3851 11.95 0.997 0.110 ! Galactose-1-phosphate uridyl transferase active profiledir:cdp_alcohol_p_transf.prf 1.90 1.68 4.50 0.05 -0.0068 -0.6638 7.67 0.999 0.151 ! CDP-alcohol phosphatidyltransferases signature. profiledir:pep_enzymes_phos_site.prf 1.77 1.58 4.50 0.05 -0.0075 -0.4283 9.53 1.004 0.127 ! PEP-utilizing enzymes phosphorylation site signa profiledir:rhodanese_1.prf 1.84 1.63 4.50 0.05 -0.0065 -0.5184 11.54 1.005 0.139 ! Rhodanese active site. profiledir:rhodanese_2.prf 1.82 1.62 4.50 0.05 -0.0055 -0.8864 9.14 1.001 0.137 ! Rhodanese C-terminal signature. profiledir:pa2_his.prf 1.90 1.68 4.50 0.05 -0.0039 -0.8939 6.86 1.006 0.149 ! Phospholipase A2 histidine active site. profiledir:pa2_asp.prf 1.81 1.61 4.50 0.05 -0.0050 -0.9181 7.22 0.999 0.135 ! Phospholipase A2 aspartic acid active site. profiledir:lipase_ser.prf 1.97 1.73 4.50 0.05 -0.0061 -0.5903 4.65 1.006 0.161 ! Lipases, serine active site. profiledir:colipase.prf 1.89 1.67 4.50 0.05 -0.0044 -0.8618 11.49 1.004 0.148 ! Colipase signature. profiledir:carboxylesterase_b.prf 1.90 1.68 4.50 0.05 -0.0050 -0.7843 8.34 0.999 0.151 ! Carboxylesterases type-B active site. profiledir:pectinesterase_2.prf 1.84 1.63 4.50 0.05 -0.0052 -0.7971 8.97 1.003 0.139 ! Pectinesterase signature 2. profiledir:alkaline_phosphatase.prf 1.87 1.65 4.50 0.05 -0.0050 -0.7188 7.34 1.002 0.145 ! Alkaline phosphatase active site. profiledir:his_acid_phosphatase.prf 1.90 1.67 4.50 0.05 -0.0049 -0.8011 6.21 1.002 0.149 ! Histidine acid phosphatases signature 1. profiledir:fbpase.prf 1.81 1.61 4.50 0.05 -0.0053 -0.7454 10.44 1.001 0.135 ! Fructose-1-6-bisphosphatase active site. profiledir:ser_thr_phosphatase.prf 1.80 1.60 4.50 0.05 -0.0060 -0.8033 7.81 1.000 0.133 ! Serine/threonine specific protein phosphatases s profiledir:tyr_phosphatase.prf 1.90 1.68 4.50 0.05 -0.0045 -0.8038 5.28 1.004 0.150 ! Tyrosine specific protein phosphatases active si profiledir:imp_1.prf 1.73 1.55 4.50 0.05 -0.0093 -0.3702 8.41 0.998 0.122 ! Inositol monophosphatase family signature 1. profiledir:imp_2.prf 1.85 1.64 4.50 0.05 -0.0067 -0.5935 7.46 0.999 0.142 ! Inositol monophosphatase family signature 2. profiledir:prokar_zn_depend_plpc.prf 1.82 1.62 4.50 0.05 -0.0062 -0.8148 11.12 0.997 0.138 ! Prokaryotic zinc-dependent phospholipase C signa profiledir:pdease_i.prf 1.81 1.60 4.50 0.05 -0.0066 -0.5970 9.10 1.001 0.134 ! 3'5'-cyclic nucleotide phosphodiesterases signat profiledir:sulfatase_2.prf 1.82 1.61 4.50 0.05 -0.0050 -0.8284 6.92 1.002 0.136 ! Sulfatases signature 2. profiledir:rnase_t2_1.prf 1.76 1.57 4.50 0.05 -0.0055 -0.7663 8.85 1.001 0.126 ! Ribonuclease T2 family histidine active site 1. profiledir:rnase_t2_2.prf 1.83 1.62 4.50 0.05 -0.0052 -0.8345 8.00 1.004 0.138 ! Ribonuclease T2 family histidine active site 2. profiledir:rnase_pancreatic.prf 1.85 1.63 4.50 0.05 -0.0043 -0.9368 6.67 1.005 0.140 ! Pancreatic ribonuclease family signature. profiledir:beta_amylase_1.prf 1.93 1.70 4.50 0.05 -0.0048 -0.8080 9.60 1.007 0.154 ! Beta-amylase signature 1. profiledir:beta_amylase_2.prf 1.85 1.64 4.50 0.05 -0.0044 -0.8531 10.89 1.005 0.141 ! Beta-amylase active site. profiledir:polygalacturonase.prf 1.80 1.60 4.50 0.05 -0.0072 -0.4528 7.36 1.000 0.134 ! Polygalacturonase active site. profiledir:lactalbumin_lysozyme.prf 1.72 1.54 4.50 0.05 -0.0072 -0.6154 10.15 1.001 0.119 ! Alpha-lactalbumin / lysozyme C signature. profiledir:alpha_galactosidase.prf 1.71 1.53 4.50 0.05 -0.0074 -0.5585 11.09 1.000 0.118 ! Alpha-galactosidase signature. profiledir:alpha_l_fucosidase.prf 1.80 1.60 4.50 0.05 -0.0055 -0.7764 11.12 1.002 0.133 ! Alpha-L-fucosidase putative active site. profiledir:glycosyl_hydrol_f1_1.prf 1.78 1.59 4.50 0.05 -0.0060 -0.6725 6.57 1.008 0.129 ! Glycosyl hydrolases family 1 active site. profiledir:glycosyl_hydrol_f1_2.prf 1.90 1.67 4.50 0.05 -0.0045 -0.8748 6.00 1.001 0.149 ! Glycosyl hydrolases family 1 N-terminal signatur profiledir:glycosyl_hydrol_f2_2.prf 1.89 1.67 4.50 0.05 -0.0069 -0.6107 6.31 1.003 0.148 ! Glycosyl hydrolases family 2 acid/base catalyst. profiledir:glycosyl_hydrol_f5.prf 1.89 1.67 4.50 0.05 -0.0054 -0.7191 4.43 0.999 0.149 ! Glycosyl hydrolases family 5 signature profiledir:glycosyl_hydrol_f6_1.prf 1.84 1.63 4.50 0.05 -0.0072 -0.5286 10.05 1.002 0.139 ! Glycosyl hydrolases family 6 signature 1. profiledir:glycosyl_hydrol_f6_2.prf 1.86 1.64 4.50 0.05 -0.0084 -0.5228 6.94 0.997 0.143 ! Glycosyl hydrolases family 6 signature 2. profiledir:glycosyl_hydrol_f9_1.prf 1.81 1.61 4.50 0.05 -0.0061 -0.6272 7.29 1.003 0.135 ! Glycosyl hydrolases family 9 active sites signat profiledir:glycosyl_hydrol_f10.prf 1.87 1.65 4.50 0.05 -0.0068 -0.7082 5.29 0.997 0.145 ! Glycosyl hydrolases family 10 active site. profiledir:glycosyl_hydrol_f17.prf 1.79 1.59 4.50 0.05 -0.0069 -0.5719 9.94 1.004 0.131 ! Glycosyl hydrolases family 17 signature. profiledir:glycosyl_hydrol_f31_1.prf 1.71 1.53 4.50 0.05 -0.0058 -0.8062 12.08 1.001 0.118 ! Glycosyl hydrolases family 31 active site. profiledir:glycosyl_hydrol_f32.prf 1.88 1.66 4.50 0.05 -0.0057 -0.6981 7.80 1.001 0.147 ! Glycosyl hydrolases family 32 active site. profiledir:map.prf 1.90 1.68 4.50 0.05 -0.0065 -0.5230 12.21 1.003 0.150 ! Methionine aminopeptidase signature. profiledir:carboxypept_ser_ser.prf 1.82 1.61 4.50 0.05 -0.0058 -0.7771 8.89 0.999 0.136 ! Serine carboxypeptidases, serine active site. profiledir:carboxypept_ser_his.prf 1.87 1.65 4.50 0.05 -0.0053 -0.7610 6.85 1.002 0.145 ! Serine carboxypeptidases, histidine active site. profiledir:carboxypept_zn_2.prf 1.88 1.66 4.50 0.05 -0.0063 -0.6208 5.33 1.000 0.147 ! Zinc carboxypeptidases, zinc-binding region 2 si profiledir:trypsin_his.prf 1.94 1.70 4.50 0.05 -0.0041 -0.9173 4.28 1.001 0.156 ! Serine proteases, trypsin family, histidine acti profiledir:trypsin_ser.prf 1.82 1.62 4.50 0.05 -0.0057 -0.6990 6.27 1.000 0.137 ! Serine proteases, trypsin family, serine active profiledir:subtilase_asp.prf 1.95 1.71 4.50 0.05 -0.0053 -0.6325 4.37 1.005 0.157 ! Serine proteases, subtilase family, aspartic aci profiledir:subtilase_his.prf 1.91 1.68 4.50 0.05 -0.0062 -0.5901 5.49 0.999 0.152 ! Serine proteases, subtilase family, histidine ac profiledir:subtilase_ser.prf 1.97 1.73 4.50 0.05 -0.0044 -0.6469 5.33 1.002 0.161 ! Serine proteases, subtilase family, serine activ profiledir:v8_his.prf 1.85 1.64 4.50 0.05 -0.0067 -0.5269 8.17 1.000 0.142 ! Serine proteases, V8 family, histidine active si profiledir:v8_ser.prf 1.85 1.64 4.50 0.05 -0.0051 -0.7110 8.13 1.007 0.140 ! Serine proteases, V8 family, serine active site. profiledir:clpp_protease_ser.prf 1.91 1.69 4.50 0.05 -0.0050 -0.7254 10.76 1.007 0.151 ! ClpP proteases serine active site. profiledir:clpp_protease_his.prf 1.85 1.64 4.50 0.05 -0.0060 -0.6675 10.85 1.003 0.141 ! ClpP proteases histidine active site. profiledir:thiol_protease_cys.prf 1.92 1.69 4.50 0.05 -0.0054 -0.7134 5.56 1.005 0.152 ! Eukaryotic thiol (cysteine) proteases cysteine a profiledir:thiol_protease_his.prf 1.68 1.51 4.50 0.05 -0.0072 -0.5630 7.73 1.000 0.114 ! Eukaryotic thiol (cysteine) proteases histidine profiledir:zinc_protease.prf 2.04 1.78 4.50 0.05 -0.0046 -0.7007 3.44 1.005 0.172 ! Neutral zinc metallopeptidases, zinc-binding reg profiledir:cysteine_switch.prf 1.85 1.64 4.50 0.05 -0.0054 -0.7891 7.02 1.002 0.142 ! Matrixins cysteine switch. profiledir:insulinase.prf 1.92 1.69 4.50 0.05 -0.0064 -0.5096 7.16 1.004 0.153 ! Insulinase family signature. profiledir:reca.prf 1.87 1.65 4.50 0.05 -0.0062 -0.6944 10.93 1.001 0.145 ! recA signature. profiledir:proteasome.prf 1.88 1.66 4.50 0.05 -0.0058 -0.7109 7.73 1.001 0.147 ! Proteasome subunits signature. profiledir:spase_i_1.prf 1.85 1.64 4.50 0.05 -0.0059 -0.6016 13.06 1.007 0.141 ! Signal peptidases I serine active site. profiledir:amidases.prf 1.98 1.74 4.50 0.05 -0.0054 -0.6320 7.32 1.004 0.163 ! Amidases signature. profiledir:asn_gln_ase.prf 1.82 1.61 4.50 0.05 -0.0066 -0.5864 7.03 0.999 0.136 ! Asparaginase / glutaminase active site. profiledir:urease.prf 1.92 1.69 4.50 0.05 -0.0052 -0.7400 10.91 1.005 0.152 ! Urease active site. profiledir:dihydroorotase_1.prf 1.96 1.72 4.50 0.05 -0.0053 -0.7268 5.62 1.009 0.159 ! Dihydroorotase signature 1. profiledir:dihydroorotase_2.prf 1.76 1.57 4.50 0.05 -0.0075 -0.5515 7.89 1.000 0.127 ! Dihydroorotase signature 2. profiledir:beta_lactamase_a.prf 1.86 1.64 4.50 0.05 -0.0060 -0.6643 7.38 1.001 0.143 ! Beta-lactamase class-A active site. profiledir:beta_lactamase_c.prf 1.87 1.66 4.50 0.05 -0.0051 -0.7454 10.04 1.003 0.145 ! Beta-lactamase class-C active site. profiledir:beta_lactamase_d.prf 1.86 1.65 4.50 0.05 -0.0055 -0.6941 7.98 1.006 0.143 ! Beta-lactamase class-D active site. profiledir:arginase_1.prf 1.93 1.69 4.50 0.05 -0.0050 -0.7911 6.75 1.002 0.154 ! Arginase and agmatinase signature 1. profiledir:arginase_2.prf 1.96 1.72 4.50 0.05 -0.0059 -0.5693 8.31 1.002 0.159 ! Arginase and agmatinase signature 2. profiledir:a_deaminase.prf 1.76 1.57 4.50 0.05 -0.0059 -0.7226 8.63 1.003 0.126 ! Adenosine and AMP deaminase signature. profiledir:ppase.prf 1.92 1.69 4.50 0.05 -0.0058 -0.6728 6.99 1.006 0.153 ! Inorganic pyrophosphatase signature. profiledir:acylphosphatase_1.prf 1.94 1.71 4.50 0.05 -0.0035 -0.9653 9.82 1.005 0.156 ! Acylphosphatase signature 1. profiledir:acylphosphatase_2.prf 1.91 1.69 4.50 0.05 -0.0061 -0.7465 10.74 1.001 0.152 ! Acylphosphatase signature 2. profiledir:atpase_alpha_beta.prf 1.98 1.74 4.50 0.05 -0.0045 -0.7029 5.02 1.005 0.163 ! ATP synthase alpha and beta subunits signature. profiledir:atpase_gamma.prf 1.93 1.70 4.50 0.05 -0.0040 -0.9031 8.39 1.002 0.155 ! ATP synthase gamma subunit signature. profiledir:atpase_delta.prf 1.44 1.33 4.50 0.05 -0.0059 -0.8129 4.10 1.000 0.073 ! ATP synthase delta (OSCP) subunit signature. profiledir:atpase_a.prf 1.88 1.66 4.50 0.05 -0.0061 -0.6272 6.33 1.004 0.146 ! ATP synthase a subunit signature. profiledir:atpase_c.prf 1.94 1.71 4.50 0.05 -0.0051 -0.5985 6.46 1.001 0.157 ! ATP synthase c subunit signature. profiledir:atpase_e1_e2.prf 1.98 1.74 4.50 0.05 -0.0040 -0.8167 5.87 1.004 0.163 ! E1-E2 ATPases phosphorylation site. profiledir:atpase_na_k_beta_1.prf 1.94 1.71 4.50 0.05 -0.0041 -0.8301 9.43 1.006 0.156 ! Sodium and potassium ATPases beta subunits signa profiledir:atpase_na_k_beta_2.prf 1.78 1.59 4.50 0.05 -0.0051 -0.7974 10.43 1.001 0.130 ! Sodium and potassium ATPases beta subunits signa profiledir:cutinase.prf 1.90 1.68 4.50 0.05 -0.0052 -0.7312 10.36 1.005 0.149 ! Cutinase, serine active site. profiledir:ompdecase.prf 1.92 1.69 4.50 0.05 -0.0045 -0.7553 6.70 1.005 0.152 ! Orotidine 5'-phosphate decarboxylase active site profiledir:pepcase_2.prf 1.84 1.63 4.50 0.05 -0.0070 -0.6666 10.64 1.004 0.140 ! Phosphoenolpyruvate carboxylase active site 2. profiledir:pepck_gtp.prf 1.85 1.64 4.50 0.05 -0.0049 -0.8115 12.04 1.000 0.142 ! Phosphoenolpyruvate carboxykinase (GTP) signatur profiledir:pepck_atp.prf 1.80 1.60 4.50 0.05 -0.0068 -0.6409 14.31 0.999 0.134 ! Phosphoenolpyruvate carboxykinase (ATP) signatur profiledir:igps.prf 1.80 1.60 4.50 0.05 -0.0071 -0.5671 7.14 0.999 0.134 ! Indole-3-glycerol phosphate synthase signature. profiledir:rubisco_large.prf 1.78 1.59 4.50 0.05 -0.0058 -0.8085 11.39 0.999 0.131 ! Ribulose bisphosphate carboxylase large chain ac profiledir:aldolase_class_i.prf 1.89 1.67 4.50 0.05 -0.0056 -0.6806 10.06 1.004 0.147 ! Fructose-bisphosphate aldolase class-I active si profiledir:citrate_synthase.prf 1.89 1.67 4.50 0.05 -0.0049 -0.7731 7.36 1.002 0.148 ! Citrate synthase signature. profiledir:isocitrate_lyase.prf 1.91 1.68 4.50 0.05 -0.0051 -0.7823 10.71 1.004 0.151 ! Isocitrate lyase signature. profiledir:dna_photolyases_1.prf 1.75 1.56 4.50 0.05 -0.0067 -0.6517 12.52 1.001 0.125 ! DNA photolyases signature 1. profiledir:dna_photolyases_2.prf 1.76 1.57 4.50 0.05 -0.0074 -0.5315 14.53 1.000 0.126 ! DNA photolyases signature 2. profiledir:euk_co2_anhydrase.prf 1.75 1.56 4.50 0.05 -0.0062 -0.6259 10.61 1.001 0.124 ! Eukaryotic-type carbonic anhydrases signature. profiledir:fumarate_lyases.prf 1.91 1.68 4.50 0.05 -0.0043 -0.7642 5.55 1.003 0.151 ! Fumarate lyases signature. profiledir:aconitase.prf 1.98 1.74 4.50 0.05 -0.0047 -0.6761 6.07 1.005 0.163 ! Aconitase family signature. profiledir:enolase.prf 1.82 1.61 4.50 0.05 -0.0067 -0.6696 10.96 1.000 0.136 ! Enolase signature. profiledir:dehydratase_ser_thr.prf 1.86 1.65 4.50 0.05 -0.0057 -0.7292 6.47 1.002 0.143 ! Serine/threonine dehydratases pyridoxal-phosphat profiledir:enoyl_coa_hydratase.prf 1.92 1.69 4.50 0.05 -0.0060 -0.5508 7.05 1.003 0.153 ! Enoyl-CoA hydratase/isomerase signature. profiledir:trp_synthase_alpha.prf 1.99 1.74 4.50 0.05 -0.0046 -0.6708 8.51 1.001 0.164 ! Tryptophan synthase alpha chain signature. profiledir:trp_synthase_beta.prf 1.90 1.68 4.50 0.05 -0.0061 -0.6196 9.44 1.005 0.150 ! Tryptophan synthase beta chain pyridoxal-phospha profiledir:d_ala_dehydratase.prf 1.85 1.64 4.50 0.05 -0.0059 -0.6348 10.11 1.005 0.141 ! Delta-aminolevulinic acid dehydratase active sit profiledir:dhdps_1.prf 1.99 1.74 4.50 0.05 -0.0067 -0.4585 8.32 1.003 0.164 ! Dihydrodipicolinate synthetase signature 1. profiledir:dhdps_2.prf 1.82 1.62 4.50 0.05 -0.0088 -0.3549 9.18 1.004 0.136 ! Dihydrodipicolinate synthetase signature 2. profiledir:pal_histidase.prf 1.92 1.69 4.50 0.05 -0.0055 -0.6812 8.18 1.004 0.152 ! Phenylalanine and histidine ammonia-lyases signa profiledir:porphobilinogen_deam.prf 1.88 1.66 4.50 0.05 -0.0065 -0.5910 8.55 1.005 0.145 ! Porphobilinogen deaminase cofactor-binding site. profiledir:guanylate_cyclases.prf 1.95 1.71 4.50 0.05 -0.0055 -0.6332 8.33 1.003 0.158 ! Guanylate cyclases signature. profiledir:ferrochelatase.prf 1.95 1.71 4.50 0.05 -0.0056 -0.7047 9.25 1.003 0.157 ! Ferrochelatase signature. profiledir:alanine_racemase.prf 1.88 1.66 4.50 0.05 -0.0063 -0.6364 8.78 1.006 0.145 ! Alanine racemase pyridoxal-phosphate attachment profiledir:aldose_1_epimerase.prf 1.88 1.66 4.50 0.05 -0.0048 -0.7994 8.33 1.005 0.146 ! Aldose 1-epimerase putative active site. profiledir:csa_ppiase.prf 1.73 1.55 4.50 0.05 -0.0066 -0.6637 10.96 0.998 0.122 ! Cyclophilin-type peptidyl-prolyl cis-trans isome profiledir:fkbp_ppiase_1.prf 1.83 1.62 4.50 0.05 -0.0086 -0.4157 9.48 0.998 0.139 ! FKBP-type peptidyl-prolyl cis-trans isomerase si profiledir:fkbp_ppiase_2.prf 1.94 1.71 4.50 0.05 -0.0043 -0.7579 8.78 1.007 0.156 ! FKBP-type peptidyl-prolyl cis-trans isomerase si profiledir:tim.prf 1.87 1.65 4.50 0.05 -0.0061 -0.6687 9.33 1.003 0.144 ! Triosephosphate isomerase active site. profiledir:xylose_isomerase_1.prf 1.91 1.68 4.50 0.05 -0.0040 -0.9140 7.71 1.003 0.151 ! Xylose isomerase signature 1. profiledir:xylose_isomerase_2.prf 1.52 1.39 4.50 0.05 -0.0104 -0.3766 13.09 0.997 0.088 ! Xylose isomerase signature 2. profiledir:p_glucose_isomerase_2.prf 1.88 1.66 4.50 0.05 -0.0062 -0.7075 10.01 1.003 0.147 ! Phosphoglucose isomerase signature 2. profiledir:pg_mutase.prf 1.80 1.60 4.50 0.05 -0.0064 -0.7319 8.18 1.004 0.133 ! Phosphoglycerate mutase family phosphohistidine profiledir:mcm.prf 1.74 1.56 4.50 0.05 -0.0075 -0.3994 14.25 1.004 0.123 ! Methylmalonyl-CoA mutase signature. profiledir:topoisomerase_i_euk.prf 1.87 1.65 4.50 0.05 -0.0066 -0.5691 7.44 1.003 0.144 ! Eukaryotic DNA topoisomerase I active site. profiledir:topoisomerase_i_prok.prf 1.81 1.61 4.50 0.05 -0.0062 -0.6836 9.23 1.002 0.135 ! Prokaryotic DNA topoisomerase I active site. profiledir:topoisomerase_ii.prf 1.73 1.55 4.50 0.05 -0.0067 -0.6231 10.27 1.006 0.120 ! DNA topoisomerase II signature. profiledir:aa_trna_ligase_i.prf 1.95 1.71 4.50 0.05 -0.0046 -0.7336 2.54 1.003 0.157 ! Aminoacyl-transfer RNA synthetases class-I signa profiledir:aa_trna_ligase_ii_1.prf 1.93 1.70 4.50 0.05 -0.0047 -0.6787 3.90 1.008 0.153 ! Aminoacyl-transfer RNA synthetases class-II sign profiledir:aa_trna_ligase_ii_2.prf 1.98 1.73 4.50 0.05 -0.0045 -0.8130 3.50 1.004 0.162 ! Aminoacyl-transfer RNA synthetases class-II sign profiledir:glna_1.prf 1.87 1.65 4.50 0.05 -0.0049 -0.7039 5.84 1.005 0.144 ! Glutamine synthetase signature 1. profiledir:glna_atp.prf 1.86 1.64 4.50 0.05 -0.0048 -0.7694 6.04 1.001 0.143 ! Glutamine synthetase putative ATP-binding region profiledir:glna_adenylation.prf 1.93 1.70 4.50 0.05 -0.0050 -0.7303 9.94 1.005 0.154 ! Glutamine synthetase class-I adenylation site. profiledir:ubiquitin_activating.prf 1.95 1.72 4.50 0.05 -0.0055 -0.7807 10.67 1.006 0.158 ! Ubiquitin-activating enzyme signature. profiledir:ubiquitin_conjugat.prf 1.82 1.61 4.50 0.05 -0.0058 -0.6970 8.61 1.001 0.136 ! Ubiquitin-conjugating enzymes active site. profiledir:argininosuccin_syn_2.prf 1.86 1.65 4.50 0.05 -0.0066 -0.6573 7.90 1.000 0.144 ! Argininosuccinate synthase signature 2. profiledir:gars.prf 1.77 1.58 4.50 0.05 -0.0072 -0.6226 10.56 1.001 0.128 ! Phosphoribosylglycinamide synthetase signature. profiledir:dna_ligase_2.prf 1.82 1.62 4.50 0.05 -0.0061 -0.6851 8.27 1.001 0.137 ! ATP-dependent DNA ligase signature 2. profiledir:ipns_1.prf 1.76 1.57 4.50 0.05 -0.0067 -0.5890 9.04 1.002 0.126 ! Isopenicillin N synthetase signature 1. profiledir:ipns_2.prf 1.94 1.70 4.50 0.05 -0.0057 -0.6706 7.91 1.007 0.155 ! Isopenicillin N synthetase signature 2. profiledir:recombinases_1.prf 1.90 1.67 4.50 0.05 -0.0031 -1.0202 5.43 1.002 0.149 ! Site-specific recombinases active site. profiledir:recombinases_2.prf 1.95 1.71 4.50 0.05 -0.0059 -0.6414 6.73 1.002 0.158 ! Site-specific recombinases signature 2. profiledir:tpp_enzymes.prf 1.81 1.61 4.50 0.05 -0.0075 -0.4433 8.34 0.998 0.135 ! Thiamine pyrophosphate enzymes signature. profiledir:biotin.prf 1.98 1.73 4.50 0.05 -0.0062 -0.6423 6.74 0.999 0.163 ! Biotin-requiring enzymes attachment site. profiledir:lipoyl.prf 1.75 1.56 4.50 0.05 -0.0064 -0.6685 2.78 0.997 0.125 ! 2-oxo acid dehydrogenases acyltransferase compon profiledir:amp_binding.prf 1.97 1.73 4.50 0.05 -0.0045 -0.7500 4.58 1.006 0.160 ! Putative AMP-binding domain signature. profiledir:cytochrome_c.prf 1.69 1.52 4.50 0.05 -0.0056 -0.9152 3.91 0.997 0.116 ! Cytochrome c family heme-binding site signature. profiledir:cytochrome_b5.prf 1.95 1.72 4.50 0.05 -0.0053 -0.7359 7.47 1.006 0.158 ! Cytochrome b5 family, heme-binding domain signat profiledir:cytochrome_b_heme.prf 1.82 1.62 4.50 0.05 -0.0060 -0.6605 7.93 1.004 0.136 ! Cytochrome b/b6 heme-ligand signature. profiledir:cytochrome_b_qo.prf 1.76 1.57 4.50 0.05 -0.0058 -0.7205 9.61 0.996 0.127 ! Cytochrome b/b6 Qo site signature. profiledir:cytochrome_b559.prf 1.78 1.59 4.50 0.05 -0.0064 -0.6140 8.69 1.002 0.130 ! Cytochrome b559 subunits heme-binding site signa profiledir:thioredoxin.prf 1.90 1.68 4.50 0.05 -0.0041 -0.9271 5.79 1.003 0.150 ! Thioredoxin family active site. profiledir:glutaredoxin.prf 1.77 1.57 4.50 0.05 -0.0058 -0.7426 7.03 1.003 0.127 ! Glutaredoxin active site. profiledir:copper_blue.prf 1.94 1.70 4.50 0.05 -0.0046 -0.8368 4.00 1.002 0.156 ! Type-1 copper (blue) proteins signature. profiledir:2fe2s_ferredoxin.prf 2.04 1.79 4.50 0.05 -0.0035 -0.8494 4.70 1.007 0.173 ! 2Fe-2S ferredoxins, iron-sulfur binding region s profiledir:4fe4s_ferredoxin.prf 1.90 1.67 4.50 0.05 -0.0037 -1.0017 5.56 1.001 0.149 ! 4Fe-4S ferredoxins, iron-sulfur binding region s profiledir:hipip.prf 1.79 1.60 4.50 0.05 -0.0048 -0.8888 7.51 1.001 0.132 ! High potential iron-sulfur proteins signature. profiledir:rieske_1.prf 1.76 1.57 4.50 0.05 -0.0056 -0.7721 9.81 1.000 0.126 ! Rieske iron-sulfur protein signature 1. profiledir:rieske_2.prf 1.77 1.58 4.50 0.05 -0.0053 -0.7642 11.47 1.002 0.128 ! Rieske iron-sulfur protein signature 2. profiledir:flavodoxin.prf 1.96 1.72 4.50 0.05 -0.0042 -0.7865 5.02 1.005 0.159 ! Flavodoxin signature. profiledir:rubredoxin.prf 1.82 1.62 4.50 0.05 -0.0044 -0.9663 7.57 1.003 0.136 ! Rubredoxin signature. profiledir:metallothionein_cl1.prf 1.92 1.69 4.50 0.05 -0.0046 -0.6284 10.40 1.006 0.152 ! Class I metallothioneins signature. profiledir:ferritin_1.prf 1.88 1.66 4.50 0.05 -0.0066 -0.6014 10.47 0.999 0.147 ! Ferritin iron-binding regions signature 1. profiledir:ferritin_2.prf 1.90 1.68 4.50 0.05 -0.0061 -0.6095 9.92 1.002 0.150 ! Ferritin iron-binding regions signature 2. profiledir:transferrin_1.prf 1.83 1.62 4.50 0.05 -0.0053 -0.8093 7.51 1.002 0.138 ! Transferrins signature 1. profiledir:transferrin_2.prf 1.82 1.61 4.50 0.05 -0.0054 -0.8336 9.58 0.998 0.137 ! Transferrins signature 2. profiledir:transferrin_3.prf 1.84 1.63 4.50 0.05 -0.0054 -0.7239 9.19 1.001 0.139 ! Transferrins signature 3. profiledir:plant_globin.prf 1.89 1.67 4.50 0.05 -0.0062 -0.6769 10.77 1.004 0.147 ! Plant hemoglobins signature. profiledir:hemerythrins.prf 1.81 1.61 4.50 0.05 -0.0047 -0.8904 8.81 1.005 0.134 ! Hemerythrins signature. profiledir:hemocyanin_1.prf 1.84 1.63 4.50 0.05 -0.0058 -0.6776 9.13 1.003 0.139 ! Arthropod hemocyanins / insect LSPs signature 1. profiledir:hemocyanin_2.prf 1.87 1.66 4.50 0.05 -0.0045 -0.8183 7.80 1.003 0.145 ! Arthropod hemocyanins / insect LSPs signature 2. profiledir:atp_bind_transport.prf 1.79 1.59 4.50 0.05 -0.0080 -0.5599 5.71 0.995 0.132 ! ATP-binding proteins `active transport' family s profiledir:bpd_transp_inn_membr.prf 1.98 1.73 4.50 0.05 -0.0056 -0.5663 4.88 1.004 0.162 ! Binding-protein-dependent transport systems inne profiledir:albumin.prf 1.99 1.75 4.50 0.05 -0.0037 -0.9023 4.96 1.004 0.165 ! Serum albumin family signature. profiledir:avidin.prf 1.82 1.61 4.50 0.05 -0.0065 -0.6594 8.56 1.001 0.136 ! Avidin / Streptavidin family signature. profiledir:cobalamin_binding.prf 1.89 1.67 4.50 0.05 -0.0046 -0.7155 8.12 1.005 0.148 ! Eukaryotic cobalamin-binding proteins signature. profiledir:fabp.prf 1.85 1.64 4.50 0.05 -0.0077 -0.5859 5.94 0.998 0.142 ! Cytosolic fatty-acid binding proteins signature. profiledir:lbp_bpi_cetp.prf 1.86 1.65 4.50 0.05 -0.0071 -0.5138 9.54 1.000 0.144 ! LBP / BPI / CETP family signature. profiledir:plant_ltp.prf 1.53 1.39 4.50 0.05 -0.0055 -0.8023 2.17 0.999 0.088 ! Plant lipid transfer proteins signature. profiledir:uteroglobin_1.prf 1.91 1.68 4.50 0.05 -0.0051 -0.7563 10.91 1.004 0.151 ! Uteroglobin family signature 1. profiledir:uteroglobin_2.prf 1.90 1.67 4.50 0.05 -0.0043 -0.9105 8.90 1.003 0.149 ! Uteroglobin family signature 2. profiledir:mitoch_carrier.prf 1.96 1.72 4.50 0.05 -0.0041 -0.7765 3.48 1.003 0.160 ! Mitochondrial energy transfer proteins signature profiledir:sugar_transport_1.prf 1.94 1.71 4.50 0.05 -0.0044 -0.6842 4.76 1.006 0.156 ! Sugar transport proteins signature 1. profiledir:sugar_transport_2.prf 1.96 1.72 4.50 0.05 -0.0041 -0.7049 5.70 1.001 0.159 ! Sugar transport proteins signature 2. profiledir:sodium_symporters_1.prf 1.95 1.71 4.50 0.05 -0.0047 -0.7251 7.31 1.000 0.158 ! Sodium symporters signature 1. profiledir:sodium_symporters_2.prf 1.84 1.63 4.50 0.05 -0.0059 -0.5673 10.17 1.003 0.139 ! Sodium symporters signature 2. profiledir:prok_sulfate_bind_1.prf 1.76 1.57 4.50 0.05 -0.0070 -0.6066 12.32 1.001 0.127 ! Prokaryotic sulfate-binding proteins signature 1 profiledir:amino_acid_permease.prf 1.86 1.65 4.50 0.05 -0.0069 -0.4839 7.71 1.000 0.144 ! Amino acid permeases signature. profiledir:aromatic_aa_permease.prf 1.87 1.66 4.50 0.05 -0.0051 -0.6986 12.58 1.004 0.145 ! Aromatic amino acids permeases signature. profiledir:anion_exchanger_1.prf 1.90 1.67 4.50 0.05 -0.0066 -0.6352 11.54 1.001 0.149 ! Anion exchangers family signature 1. profiledir:anion_exchanger_2.prf 1.91 1.68 4.50 0.05 -0.0051 -0.6607 12.40 1.006 0.150 ! Anion exchangers family signature 2. profiledir:neurotransm_transp_1.prf 1.86 1.65 4.50 0.05 -0.0050 -0.6914 13.59 1.006 0.142 ! Neurotransmitters transporters signature 1. profiledir:gram_neg_porin.prf 1.88 1.66 4.50 0.05 -0.0075 -0.5163 7.85 1.002 0.146 ! General diffusion gram-negative porins signature profiledir:eukaryotic_porin.prf 1.81 1.60 4.50 0.05 -0.0098 -0.2646 11.46 1.001 0.134 ! Eukaryotic porin signature. profiledir:igf_binding.prf 1.88 1.66 4.50 0.05 -0.0050 -0.6946 9.47 1.005 0.146 ! Insulin-like growth factor binding proteins sign profiledir:actins_2.prf 1.79 1.59 4.50 0.05 -0.0050 -0.8565 11.09 1.002 0.131 ! Actins signature 2. profiledir:clathrin_light_chn_1.prf 1.91 1.69 4.50 0.05 -0.0054 -0.6112 11.25 1.007 0.151 ! Clathrin light chain signature 1. profiledir:clathrin_light_chn_2.prf 1.91 1.68 4.50 0.05 -0.0050 -0.8076 8.40 1.005 0.151 ! Clathrin light chain signature 2. profiledir:clusterin_1.prf 1.89 1.67 4.50 0.05 -0.0040 -0.9364 12.29 1.004 0.147 ! Clusterin signature 1. profiledir:clusterin_2.prf 1.91 1.68 4.50 0.05 -0.0038 -0.8893 11.18 1.004 0.151 ! Clusterin signature 2. profiledir:connexins_1.prf 1.89 1.67 4.50 0.05 -0.0047 -0.8379 10.92 1.004 0.148 ! Connexins signature 1. profiledir:connexins_2.prf 1.83 1.62 4.50 0.05 -0.0048 -0.8281 11.09 0.999 0.139 ! Connexins signature 2. profiledir:crystallin_betagamma.prf 1.94 1.71 4.50 0.05 -0.0055 -0.7027 3.12 1.001 0.157 ! Crystallins beta and gamma 'Greek key' motif sig profiledir:dynamin.prf 1.82 1.61 4.50 0.05 -0.0064 -0.6085 11.88 1.006 0.135 ! Dynamin family signature. profiledir:if.prf 1.96 1.72 4.50 0.05 -0.0046 -0.7435 6.89 1.004 0.160 ! Intermediate filaments signature. profiledir:kinesin_motor_domain.prf 1.85 1.63 4.50 0.05 -0.0057 -0.7344 7.95 1.005 0.140 ! Kinesin motor domain signature. profiledir:myelin_mbp.prf 1.87 1.65 4.50 0.05 -0.0060 -0.6521 9.50 1.005 0.144 ! Myelin basic protein signature. profiledir:myelin_p0.prf 1.86 1.65 4.50 0.05 -0.0039 -0.8932 11.06 0.999 0.144 ! Myelin P0 protein signature. profiledir:myelin_plp.prf 1.92 1.69 4.50 0.05 -0.0050 -0.8423 12.59 1.000 0.153 ! Myelin proteolipid protein signature. profiledir:neuromodulin_2.prf 2.00 1.75 4.50 0.05 -0.0058 -0.6174 10.67 1.002 0.166 ! Neuromodulin (GAP-43) signature 2. profiledir:surfact_palmytoyl.prf 1.63 1.48 4.50 0.05 -0.0078 -0.3190 15.45 0.999 0.106 ! Surfactant associated polypeptide SP-C palmitoyl profiledir:synapsin_1.prf 1.87 1.65 4.50 0.05 -0.0043 -0.8956 10.87 1.006 0.144 ! Synapsins signature 1. profiledir:synapsin_2.prf 1.82 1.62 4.50 0.05 -0.0057 -0.7058 13.69 1.002 0.137 ! Synapsins signature 2. profiledir:synaptobrevin.prf 1.93 1.70 4.50 0.05 -0.0062 -0.5712 13.20 1.003 0.154 ! Synaptobrevin signature. profiledir:synaptop.prf 1.86 1.64 4.50 0.05 -0.0051 -0.7921 12.71 1.004 0.142 ! Synaptophysin / synaptoporin signature. profiledir:tropomyosin.prf 1.99 1.74 4.50 0.05 -0.0047 -0.7299 10.44 1.002 0.164 ! Tropomyosins signature. profiledir:tau_map.prf 1.88 1.66 4.50 0.05 -0.0066 -0.5980 8.62 1.002 0.147 ! Tau and MAP proteins repeated region signature. profiledir:map1b_neuraxin.prf 1.56 1.42 4.50 0.05 -0.0059 -0.5504 13.76 0.999 0.094 ! Neuraxin and MAP1B proteins repeated region sign profiledir:f_actin_capping_beta.prf 1.85 1.64 4.50 0.05 -0.0054 -0.7567 11.51 1.003 0.141 ! F-actin capping protein beta subunit signature. profiledir:vinculin_1.prf 2.00 1.75 4.50 0.05 -0.0057 -0.5881 8.05 1.003 0.166 ! Vinculin family talin-binding region signature. profiledir:vinculin_2.prf 1.86 1.65 4.50 0.05 -0.0067 -0.5592 7.61 1.006 0.143 ! Vinculin repeated domain signature. profiledir:a4_extra.prf 1.91 1.68 4.50 0.05 -0.0051 -0.8419 9.86 1.001 0.151 ! Amyloidogenic glycoprotein extracellular domain profiledir:a4_intra.prf 1.92 1.69 4.50 0.05 -0.0041 -0.9515 8.78 1.006 0.152 ! Amyloidogenic glycoprotein intracellular domain profiledir:cadherin.prf 1.99 1.74 4.50 0.05 -0.0047 -0.6994 5.30 1.003 0.164 ! Cadherins extracellular repeated domain signatur profiledir:cuticle_flexible.prf 1.81 1.61 4.50 0.05 -0.0068 -0.4909 10.98 0.999 0.135 ! Insect flexible cuticle proteins signature. profiledir:gas_vesicle_a_1.prf 1.94 1.71 4.50 0.05 -0.0051 -0.7099 7.74 1.004 0.156 ! Gas vesicles protein GVPa signature 1. profiledir:gas_vesicle_a_2.prf 1.94 1.71 4.50 0.05 -0.0054 -0.6444 7.64 1.003 0.156 ! Gas vesicles protein GVPa signature 2. profiledir:gas_vesicle_c.prf 1.86 1.65 4.50 0.05 -0.0073 -0.4681 10.12 1.002 0.143 ! Gas vesicles protein GVPc repeated domain signat profiledir:flagella_bb_rod.prf 1.95 1.71 4.50 0.05 -0.0044 -0.7522 5.12 0.999 0.159 ! Flagella basal body rod proteins signature. profiledir:icosah_vir_coat_s.prf 1.94 1.71 4.50 0.05 -0.0060 -0.6394 6.83 1.002 0.157 ! Plant viruses icosahedral capsid proteins 'S' re profiledir:potex_carlavirus_coat.prf 1.94 1.70 4.50 0.05 -0.0058 -0.6263 9.99 1.007 0.155 ! Potexviruses and carlaviruses coat protein signa profiledir:neurotr_ion_channel.prf 1.85 1.63 4.50 0.05 -0.0044 -0.8795 7.04 0.996 0.142 ! Neurotransmitter-gated ion-channels signature. profiledir:g_protein_receptor.prf 1.94 1.70 4.50 0.05 -0.0049 -0.7616 2.90 1.001 0.156 ! G-protein coupled receptors signature. profiledir:g_protein_recep_f2_1.prf 1.84 1.63 4.50 0.05 -0.0066 -0.6290 9.61 1.002 0.139 ! G-protein coupled receptors family 2 signature 1 profiledir:g_protein_recep_f2_2.prf 1.85 1.63 4.50 0.05 -0.0041 -0.9261 11.08 0.999 0.141 ! G-protein coupled receptors family 2 signature 2 profiledir:opsin.prf 1.97 1.73 4.50 0.05 -0.0046 -0.7124 6.31 1.002 0.162 ! Visual pigments (opsins) retinal binding site. profiledir:bacterial_opsin.prf 1.86 1.65 4.50 0.05 -0.0064 -0.5806 8.82 1.003 0.143 ! Bacterial rhodopsins retinal binding site. profiledir:receptor_tyr_kin_ii.prf 1.91 1.69 4.50 0.05 -0.0051 -0.7760 10.47 1.001 0.152 ! Receptor tyrosine kinase class II signature. profiledir:receptor_tyr_kin_iii.prf 1.88 1.66 4.50 0.05 -0.0043 -0.8935 7.03 1.000 0.147 ! Receptor tyrosine kinase class III signature. profiledir:receptor_cytokines_1.prf 1.80 1.60 4.50 0.05 -0.0047 -0.8882 3.72 0.999 0.134 ! Growth factor and cytokines receptors family sig profiledir:receptor_cytokines_2.prf 1.77 1.58 4.50 0.05 -0.0042 -0.9717 6.22 1.000 0.128 ! Growth factor and cytokines receptors family sig profiledir:integrin_alpha.prf 2.01 1.76 4.50 0.05 -0.0043 -0.7687 7.40 1.006 0.167 ! Integrins alpha chain signature. profiledir:integrin_beta.prf 1.97 1.73 4.50 0.05 -0.0033 -0.8815 6.51 1.007 0.161 ! Integrins beta chain cysteine-rich domain signat profiledir:anf_receptors.prf 1.93 1.70 4.50 0.05 -0.0057 -0.6137 10.88 1.004 0.154 ! Natriuretic peptides receptors signature. profiledir:reaction_center.prf 1.90 1.68 4.50 0.05 -0.0065 -0.5060 7.58 0.999 0.151 ! Photosynthetic reaction center proteins signatur profiledir:photosystem_i_psaab.prf 1.86 1.64 4.50 0.05 -0.0046 -0.8798 12.29 1.004 0.142 ! Photosystem I psaA and psaB proteins signature. profiledir:phytochrome.prf 1.92 1.69 4.50 0.05 -0.0050 -0.6987 10.44 1.008 0.152 ! Phytochrome chromophore attachment site. profiledir:speract_receptor.prf 1.86 1.64 4.50 0.05 -0.0068 -0.5099 9.92 0.998 0.143 ! Speract receptor repeated domain signature. profiledir:type2_membran_antigen.prf 1.98 1.73 4.50 0.05 -0.0041 -0.6998 8.45 1.003 0.162 ! Type-II membrane antigens family signature. profiledir:chemotaxis_transducer.prf 2.00 1.75 4.50 0.05 -0.0069 -0.4146 11.77 1.004 0.166 ! Bacterial chemotaxis sensory transducers signatu profiledir:hbgf_fgf.prf 1.97 1.73 4.50 0.05 -0.0049 -0.7210 8.75 1.007 0.160 ! HBGF/FGF family signature. profiledir:ptn_mk_1.prf 1.77 1.58 4.50 0.05 -0.0070 -0.4817 14.40 1.002 0.128 ! PTN/MK heparin-binding protein family signature profiledir:ptn_mk_2.prf 1.78 1.59 4.50 0.05 -0.0076 -0.5017 14.16 0.998 0.131 ! PTN/MK heparin-binding protein family signature profiledir:ngf.prf 1.73 1.55 4.50 0.05 -0.0060 -0.6617 11.54 1.001 0.121 ! Nerve growth factor family signature. profiledir:pdgf.prf 1.87 1.65 4.50 0.05 -0.0045 -0.8383 9.65 1.007 0.144 ! Platelet-derived growth factor (PDGF) family sig profiledir:small_cytokines_cxc.prf 1.89 1.67 4.50 0.05 -0.0052 -0.6588 7.79 1.007 0.147 ! Small cytokines (intercrine/chemokine) C-x-C sub profiledir:small_cytokines_cc.prf 1.87 1.65 4.50 0.05 -0.0052 -0.7529 8.91 1.007 0.143 ! Small cytokines (intercrine/chemokine) C-C subfa profiledir:tgf_beta.prf 1.77 1.58 4.50 0.05 -0.0054 -0.7977 8.19 1.003 0.128 ! TGF-beta family signature. profiledir:tnf.prf 1.82 1.61 4.50 0.05 -0.0060 -0.6349 11.54 1.005 0.135 ! TNF family signature. profiledir:wnt1.prf 1.90 1.67 4.50 0.05 -0.0049 -0.8099 9.82 1.004 0.149 ! Wnt-1 family signature. profiledir:interferon_alphabeta.prf 1.94 1.70 4.50 0.05 -0.0043 -0.8160 7.97 1.007 0.155 ! Interferon alpha and beta family signature. profiledir:interleukin_1.prf 1.91 1.69 4.50 0.05 -0.0051 -0.6366 7.74 1.007 0.151 ! Interleukin-1 signature. profiledir:interleukin_2.prf 1.81 1.61 4.50 0.05 -0.0067 -0.6388 13.11 1.003 0.134 ! Interleukin-2 signature. profiledir:interleukin_6.prf 1.85 1.63 4.50 0.05 -0.0079 -0.4041 9.27 1.000 0.141 ! Interleukin-6 / G-CSF / MGF signature. profiledir:lif_osm.prf 1.67 1.50 4.50 0.05 -0.0074 -0.6227 4.29 0.997 0.112 ! LIF / OSM family signature. profiledir:akh.prf 1.82 1.61 4.50 0.05 -0.0063 -0.7914 10.27 0.998 0.137 ! Adipokinetic hormone family signature. profiledir:bombesin.prf 1.90 1.67 4.50 0.05 -0.0046 -0.8021 7.49 1.003 0.149 ! Bombesin-like peptides family signature. profiledir:calcitonin.prf 1.72 1.54 4.50 0.05 -0.0080 -0.3926 9.58 1.003 0.119 ! Calcitonin / CGRP / IAPP family signature. profiledir:crf.prf 1.88 1.66 4.50 0.05 -0.0054 -0.6589 6.47 1.008 0.145 ! Corticotropin-releasing factor family signature. profiledir:granins_1.prf 1.98 1.73 4.50 0.05 -0.0035 -0.8449 6.70 1.001 0.163 ! Granins signature 1. profiledir:granins_2.prf 1.93 1.70 4.50 0.05 -0.0054 -0.6219 10.22 1.006 0.154 ! Granins signature 2. profiledir:gastrin.prf 1.82 1.61 4.50 0.05 -0.0038 -0.9498 7.43 1.002 0.136 ! Gastrin / cholecystokinin family signature. profiledir:glyco_hormone_beta_1.prf 1.84 1.63 4.50 0.05 -0.0039 -0.8854 7.94 1.003 0.140 ! Glycoprotein hormones beta chain signature 1. profiledir:glyco_hormone_beta_2.prf 1.88 1.66 4.50 0.05 -0.0035 -0.9057 8.29 1.006 0.145 ! Glycoprotein hormones beta chain signature 2. profiledir:gnrh.prf 1.88 1.66 4.50 0.05 -0.0048 -0.9370 12.78 0.996 0.148 ! Gonadotropin-releasing hormones signature. profiledir:insulin.prf 1.95 1.71 4.50 0.05 -0.0024 -1.0590 5.95 1.002 0.158 ! Insulin family signature. profiledir:natriuretic_peptide.prf 1.82 1.62 4.50 0.05 -0.0053 -0.8971 8.56 1.003 0.136 ! Natriuretic peptides signature. profiledir:neurohypophys_horm.prf 1.86 1.65 4.50 0.05 -0.0049 -0.8438 10.54 1.006 0.142 ! Neurohypophysial hormones signature. profiledir:pancreatic_hormone.prf 1.95 1.71 4.50 0.05 -0.0041 -0.8768 8.40 1.003 0.157 ! Pancreatic hormone family signature. profiledir:parathyroid.prf 1.78 1.59 4.50 0.05 -0.0074 -0.6376 10.07 1.001 0.130 ! Parathyroid hormone family signature. profiledir:somatotropin_1.prf 1.95 1.71 4.50 0.05 -0.0049 -0.8268 3.09 1.004 0.157 ! Somatotropin, prolactin and related hormones sig profiledir:somatotropin_2.prf 1.90 1.68 4.50 0.05 -0.0037 -0.9805 5.42 1.005 0.149 ! Somatotropin, prolactin and related hormones sig profiledir:thymosin_b4.prf 1.99 1.75 4.50 0.05 -0.0037 -0.8079 10.69 1.008 0.164 ! Thymosin beta-4 family signature. profiledir:cecropin.prf 1.78 1.59 4.50 0.05 -0.0075 -0.5197 7.09 1.002 0.130 ! Cecropin family signature. profiledir:defensin.prf 1.88 1.66 4.50 0.05 -0.0037 -1.0912 6.51 1.003 0.147 ! Mammalian defensins signature. profiledir:insect_defensins.prf 1.72 1.54 4.50 0.05 -0.0055 -0.8239 12.43 1.003 0.119 ! Insect defensins signature. profiledir:endothelin.prf 1.94 1.71 4.50 0.05 -0.0041 -0.8656 6.35 1.008 0.155 ! Endothelins / sarafotoxins signature. profiledir:thionin.prf 1.86 1.65 4.50 0.05 -0.0040 -0.9247 8.33 1.007 0.142 ! Plant thionins signature. profiledir:snake_toxin.prf 1.87 1.65 4.50 0.05 -0.0032 -1.0714 6.43 1.001 0.145 ! Snake toxins signature. profiledir:myotoxins.prf 1.84 1.63 4.50 0.05 -0.0040 -0.9561 12.19 1.004 0.139 ! Myotoxins signature. profiledir:enterotoxin_h_stable.prf 1.79 1.59 4.50 0.05 -0.0039 -1.0211 8.21 1.001 0.131 ! Heat-stable enterotoxins signature. profiledir:aerolysin.prf 1.83 1.62 4.50 0.05 -0.0044 -0.8135 9.39 1.004 0.137 ! Aerolysin type toxins signature. profiledir:channel_colicin.prf 1.94 1.71 4.50 0.05 -0.0056 -0.6038 7.36 1.008 0.156 ! Channel forming colicins signature. profiledir:hok_gef.prf 1.89 1.67 4.50 0.05 -0.0054 -0.7284 8.83 1.004 0.148 ! Hok/gef family cell toxic proteins signature. profiledir:staph_strep_toxin_1.prf 1.84 1.63 4.50 0.05 -0.0049 -0.8546 6.80 1.000 0.140 ! Staphyloccocal enterotoxin/Streptococcal pyrogen profiledir:staph_strep_toxin_2.prf 1.84 1.63 4.50 0.05 -0.0062 -0.6804 8.73 0.999 0.140 ! Staphyloccocal enterotoxin/Streptococcal pyrogen profiledir:thiol_cytolysins.prf 1.87 1.66 4.50 0.05 -0.0060 -0.6701 11.26 1.003 0.145 ! Thiol-activated cytolysins signature. profiledir:mac_perforin.prf 1.83 1.62 4.50 0.05 -0.0052 -0.7718 8.70 1.003 0.137 ! Membrane attack complex components / perforin si profiledir:bpti_kunitz.prf 1.88 1.66 4.50 0.05 -0.0034 -0.9932 7.44 1.002 0.146 ! Pancreatic trypsin inhibitor (Kunitz) family sig profiledir:bowman_birk.prf 1.89 1.67 4.50 0.05 -0.0032 -0.9686 7.70 1.003 0.148 ! Bowman-Birk serine protease inhibitors family si profiledir:kazal.prf 1.94 1.71 4.50 0.05 -0.0028 -0.9709 6.58 1.003 0.156 ! Kazal serine protease inhibitors family signatur profiledir:soybean_kunitz.prf 1.80 1.60 4.50 0.05 -0.0061 -0.6941 6.12 1.002 0.133 ! Soybean trypsin inhibitor (Kunitz) protease inhi profiledir:serpin.prf 1.78 1.58 4.50 0.05 -0.0053 -0.7908 4.99 0.997 0.130 ! Serpins signature. profiledir:potato_inhibitor.prf 1.86 1.64 4.50 0.05 -0.0058 -0.7233 5.91 0.999 0.143 ! Potato inhibitor I family signature. profiledir:squash_inhibitor.prf 1.83 1.62 4.50 0.05 -0.0032 -1.1181 8.58 1.003 0.137 ! Squash family of serine protease inhibitors sign profiledir:cystatin.prf 1.96 1.72 4.50 0.05 -0.0051 -0.6707 4.97 1.008 0.159 ! Cysteine proteases inhibitors signature. profiledir:timp.prf 1.96 1.72 4.50 0.05 -0.0040 -0.9108 10.69 1.004 0.160 ! Tissue inhibitors of metalloproteinases signatur profiledir:cereal_tryp_amyl_inh.prf 1.87 1.65 4.50 0.05 -0.0052 -0.7059 6.70 1.003 0.144 ! Cereal trypsin/alpha-amylase inhibitors family s profiledir:alpha_2_macroglobulin.prf 1.76 1.57 4.50 0.05 -0.0064 -0.6694 8.14 1.003 0.126 ! Alpha-2-macroglobulin family thiolester region s profiledir:disintegrins.prf 1.69 1.52 4.50 0.05 -0.0060 -0.6340 12.98 0.999 0.115 ! Disintegrins signature. profiledir:lambda_phage_ciii.prf 1.75 1.56 4.50 0.05 -0.0077 -0.5071 11.19 1.001 0.124 ! Lambdoid phages regulatory protein CIII signatur profiledir:pentaxin.prf 1.84 1.63 4.50 0.05 -0.0045 -0.9150 7.34 0.997 0.141 ! Pentaxin family signature. profiledir:ig_mhc.prf 2.02 1.76 4.50 0.05 -0.0054 -0.7635 3.37 1.001 0.169 ! Immunoglobulins and major histocompatibility com profiledir:pili_chaperone.prf 1.74 1.55 4.50 0.05 -0.0075 -0.5177 11.52 0.997 0.123 ! Gram-negative pili assembly chaperone signature. profiledir:prion_1.prf 1.65 1.48 4.50 0.05 -0.0060 -0.4816 16.90 0.998 0.108 ! Prion protein signature 1. profiledir:cyclins.prf 1.79 1.59 4.50 0.05 -0.0056 -0.7702 5.93 0.996 0.132 ! Cyclins signature. profiledir:pcna.prf 1.90 1.67 4.50 0.05 -0.0045 -0.8404 8.83 1.002 0.149 ! Proliferating cell nuclear antigen signature. profiledir:arrestins.prf 1.89 1.67 4.50 0.05 -0.0061 -0.6218 10.09 1.001 0.148 ! Arrestins signature. profiledir:chaperonins_cpn60.prf 1.98 1.74 4.50 0.05 -0.0049 -0.6365 8.84 1.007 0.162 ! Chaperonins cpn60 signature. profiledir:chaperonins_cpn10.prf 1.73 1.54 4.50 0.05 -0.0067 -0.7976 7.48 0.999 0.121 ! Chaperonins cpn10 signature. profiledir:hsp70_1.prf 1.87 1.65 4.50 0.05 -0.0047 -0.8057 8.02 1.001 0.144 ! Heat shock hsp70 proteins family signature 1. profiledir:hsp70_2.prf 1.62 1.46 4.50 0.05 -0.0085 -0.3509 14.58 0.997 0.103 ! Heat shock hsp70 proteins family signature 2. profiledir:hsp90.prf 1.84 1.63 4.50 0.05 -0.0044 -0.8746 11.54 1.002 0.140 ! Heat shock hsp90 proteins family signature. profiledir:dnaj_nter.prf 1.89 1.67 4.50 0.05 -0.0063 -0.6597 7.59 1.000 0.148 ! Nt-dnaJ domain signature. profiledir:dnaj_cxxcxgxg.prf 1.94 1.71 4.50 0.05 -0.0046 -0.7032 7.93 1.005 0.156 ! CXXCXGXG dnaJ domain signature. profiledir:cdc48_pas1_sec18.prf 1.79 1.59 4.50 0.05 -0.0022 -1.2065 0.96 1.009 0.130 ! CDC48 / PAS1 / SEC18 family signature. profiledir:g_beta_repeats.prf 1.73 1.55 4.50 0.05 -0.0038 -1.0406 2.95 1.003 0.121 ! Beta-transducin family Trp-Asp repeats signature profiledir:ras_gtpase_activ.prf 1.84 1.63 4.50 0.05 -0.0050 -0.7408 9.25 1.004 0.140 ! Ras GTPase-activating proteins signature. profiledir:stathmin.prf 1.87 1.65 4.50 0.05 -0.0056 -0.7032 12.50 1.002 0.144 ! Stathmin family signature. profiledir:srp54.prf 1.92 1.69 4.50 0.05 -0.0060 -0.5717 8.35 1.004 0.152 ! SRP54-type proteins GTP-binding domain signature profiledir:efactor_gtp.prf 1.98 1.74 4.50 0.05 -0.0045 -0.6979 4.73 1.004 0.163 ! GTP-binding elongation factors signature. profiledir:if5a_hypusine.prf 1.91 1.69 4.50 0.05 -0.0046 -0.8798 11.06 1.002 0.152 ! Eukaryotic initiation factor 5A hypusine signatu profiledir:s100_cabp.prf 1.92 1.69 4.50 0.05 -0.0059 -0.7284 6.79 0.999 0.154 ! S-100/ICaBP type calcium binding protein signatu profiledir:hemolysin_calcium.prf 1.85 1.64 4.50 0.05 -0.0050 -0.6280 9.32 1.005 0.141 ! Hemolysin-type putative calcium-binding region s profiledir:hlyd_family.prf 1.94 1.70 4.50 0.05 -0.0051 -0.6686 2.95 1.006 0.155 ! HlyD family secretion proteins signature. profiledir:pii_glnb_ump.prf 1.90 1.68 4.50 0.05 -0.0053 -0.7581 10.97 1.003 0.150 ! P-II protein urydylation site. profiledir:pii_glnb_cter.prf 1.95 1.72 4.50 0.05 -0.0046 -0.6821 9.18 1.011 0.157 ! P-II protein C-terminal region signature. profiledir:casein_alpha_beta.prf 2.01 1.75 4.50 0.05 -0.0057 -0.8912 7.03 1.003 0.167 ! Caseins alpha/beta signature. profiledir:lectin_legume_beta.prf 1.70 1.52 4.50 0.05 -0.0067 -0.6218 8.11 1.002 0.116 ! Legume lectins beta-chain signature. profiledir:lectin_legume_alpha.prf 1.78 1.59 4.50 0.05 -0.0054 -0.7651 9.30 1.003 0.130 ! Legume lectins alpha-chain signature. profiledir:lectin_galactoside.prf 1.59 1.44 4.50 0.05 -0.0076 -0.4952 14.48 1.003 0.097 ! Vertebrate galactoside-binding lectin signature. profiledir:lamp_1.prf 1.92 1.69 4.50 0.05 -0.0067 -0.5732 5.99 1.003 0.153 ! Lysosome-associated membrane glycoproteins dupli profiledir:lamp_2.prf 1.96 1.72 4.50 0.05 -0.0043 -0.8910 9.48 1.003 0.159 ! Lysosome-associated membrane glycoproteins cytop profiledir:glycophorin_a.prf 1.97 1.73 4.50 0.05 -0.0058 -0.6393 9.88 1.006 0.161 ! Glycophorin A signature. profiledir:svp_i.prf 1.98 1.73 4.50 0.05 -0.0054 -0.6614 9.56 1.003 0.162 ! Seminal vesicle protein I repeats signature. profiledir:svp_ii.prf 1.68 1.51 4.50 0.05 -0.0066 -0.4904 13.70 1.001 0.113 ! Seminal vesicle protein II repeats signature. profiledir:tissue_factor.prf 1.85 1.64 4.50 0.05 -0.0056 -0.7075 12.53 1.004 0.141 ! Tissue factor signature. profiledir:hcp.prf 1.99 1.74 4.50 0.05 -0.0070 -0.2391 12.78 1.006 0.164 ! HCP repeats signature. profiledir:ice_nucleation.prf 2.00 1.75 4.50 0.05 -0.0051 -0.6359 9.16 1.003 0.166 ! Bacterial ice-nucleation proteins octamer repeat profiledir:ftsw_roda_spove.prf 1.82 1.61 4.50 0.05 -0.0052 -0.7420 11.49 1.002 0.136 ! Cell cycle proteins ftsW / rodA / spoVE signatur profiledir:staphylocoagulase.prf 1.74 1.56 4.50 0.05 -0.0071 -0.2947 15.65 1.003 0.123 ! Staphylocoagulase repeat signature. profiledir:11s_seed_storage.prf 1.92 1.69 4.50 0.05 -0.0040 -0.7972 6.42 1.005 0.152 ! 11-S plant seed storage proteins signature. profiledir:dehydrin.prf 1.99 1.74 4.50 0.05 -0.0066 -0.4242 9.85 1.003 0.164 ! Dehydrins signature. profiledir:small_hydr_plant_seed.prf 1.95 1.71 4.50 0.05 -0.0043 -0.7598 10.94 1.005 0.157 ! Small hydrophilic plant seed proteins signature. profiledir:pathogenesis_betvi.prf 1.86 1.65 4.50 0.05 -0.0062 -0.6069 8.77 1.005 0.143 ! Pathogenesis-related proteins BetvI family signa profiledir:thaumatin.prf 1.92 1.69 4.50 0.05 -0.0064 -0.6839 11.26 1.001 0.153 ! Thaumatin family signature.